Results 41 to 50 of about 1,127,448 (336)

Taxane-Induced Upper Gastrointestinal Bleeding

Case Reports in Oncology, 2021
Docetaxel is a taxane, which is a class of chemotherapy agent used in the treatment of multiple malignancies. It is known to have gastrointestinal side effects which can range from mild symptoms such as nausea and diarrhea to more severe complications ...
Yao Liu, Brent Hiramoto, Janet Kwok, Ahmad Ibrahim, Sergei Tatishchev, Irene Kang, Rushabh Modi   +6 more
doaj   +1 more source

The diagnostic ability of SPECT/CT fusion imaging for gastrointestinal bleeding: a retrospective study

BMC Gastroenterology, 2018
Background Blood loss from the gastrointestinal tract can be an acute and life-threatening event. For the treatment of gastrointestinal bleeding, it is important to accurately detect gastrointestinal bleeding and to localize the sites of bleeding.
Yoichi Otomi, Hideki Otsuka, Kaori Terazawa, Moriaki Yamanaka, Yuki Obama, Maki Arase, Maki Otomo, Saho Irahara, Michiko Kubo, Naoto Uyama, Takashi Abe, Masafumi Harada   +11 more
doaj   +1 more source

Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

New England Journal of Medicine, 2018
BACKGROUND Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear.
M. Krag, Søren Marker, A. Perner, J. Wetterslev, M. Wise, J. Schefold, F. Keus, A. Guttormsen, S. Bendel, M. Borthwick, T. Lange, B. Rasmussen, M. Siegemund, H. Bundgaard, T. Elkmann, Jacob V Jensen, R. D. Nielsen, L. Liboriussen, M. Bestle, Jeanie M Elkjær, D. F. Palmqvist, M. Bäcklund, J. Laake, P. M. Bådstøløkken, J. Grönlund, Olena Breum, A. Walli, R. Winding, S. Iversen, I. Jarnvig, J. White, B. Brand, M. Madsen, Lars Quist, K. Thornberg, A. Møller, J. Wiis, A. Granholm, C. T. Anthon, T. Meyhoff, P. B. Hjortrup, S. Aagaard, J. B. Andreasen, C. Sørensen, Pernille Haure, Jacob Hauge, A. Hollinger, Jonas D. Scheuzger, D. Tuchscherer, Thierry Vuilliomenet, J. Takala, S. Jakob, M. Vang, Kim B. Pælestik, K. L. Andersen, I. V. D. van der Horst, W. Dieperink, J. Fjølner, C. Kjer, Christine Sølling, C. Sølling, Johanna Karttunen, Matt Morgan, Brit Sjøbø, Janus Engstrøm, B. Agerholm-Larsen, M. Møller   +66 more
semanticscholar   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

Growth Differentiation Factor 15 and Risk of Bleeding Events: The Atherosclerosis Risk in Communities Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background GDF15 (growth differentiation factor 15) is a potent predictor of bleeding in people with cardiovascular disease. However, whether GDF15 is associated with bleeding in individuals without a history of cardiovascular disease is unknown. Methods
Lena Mathews, Xiao Hu, Ning Ding, Junichi Ishigami, Mahmoud Al Rifai, Ron C. Hoogeveen, Josef Coresh, Christie M. Ballantyne, Elizabeth Selvin, Kunihiro Matsushita   +9 more
doaj   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

Engineering a Human‐Sized Common Bile Duct Prototype with Regenerative Potential: In Vitro Evaluation of Mechanics, Function, Degradation, and Immune Modulation

Advanced Healthcare Materials, EarlyView.
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua, Marianna Barbuto, Matteo Calligaris, Roberto Di Gesù, Duilio Pagano, Rosalia Busà, Salvatore Gruttadauria, Simone Dario Scilabra, Antonio D'Amore, Maria Giovanna Francipane   +9 more
wiley   +1 more source

Frailty and risk of gastrointestinal bleeding: a prospective cohort study based on UK biobank

Frontiers in Public Health
IntroductionFrailty has been associated with various diseases. However, its impact on gastrointestinal bleeding (GIB) remains largely unexplored. This study investigates the relationship between frailty and the incidence of gastrointestinal bleeding ...
Chenao Zhang, Chenao Zhang, Qiming Huang, Xingyu Liu, Jiren Wang, Junyan Wang, Jian Song, Rong Song, Hong Su, Qiao Mei   +9 more
doaj   +1 more source

A rare cause of recurrent gastrointestinal bleeding: mesenteric hemangioma

World Journal of Emergency Surgery, 2009
Lower gastrointestinal hemorrhage accounts for approximately 20% of gastrointestinal hemorrhage. The most common causes of lower gastrointestinal hemorrhage in adults are diverticular disease, inflammatory bowel disease, benign anorectal diseases ...
Zeytunlu Murat, Ersoz Galip, Yilmaz Funda, Ozsan Nazan, Unver Mutlu, Ibis Cem, Ulas Murat, Kazimi Mircelal, Kilic Murat, Coker Ahmet   +9 more
doaj   +1 more source

Asia-Pacific working group consensus on non-variceal upper gastrointestinal bleeding: an update 2018

Gut, 2018
Non-variceal upper gastrointestinal bleeding remains an important emergency condition, leading to significant morbidity and mortality. As endoscopic therapy is the ’gold standard' of management, treatment of these patients can be considered in three ...
J. Sung, P. Chiu, F. Chan, J. Lau, K. Goh, Lawrence HY Ho, Hwoon-young Jung, J. Sollano, T. Gotoda, N. Reddy, Rajvinder Singh, K. Sugano, Kai‐chun Wu, Chun-Yin Wu, D. Bjorkman, D. Jensen, E. Kuipers, Á. Lanas   +17 more
semanticscholar   +1 more source