Results 71 to 80 of about 1,127,448 (336)

GASTROINTESTINAL BLEEDING

open access: yesEmergency Medicine Clinics of North America, 1996
A systemic approach must be taken with both upper and lower gastrointestinal bleeding. The first priority is stabilization. Once this has been achieved, and in patients who present with stable vital signs, a systematic approach to diagnosis and management must be followed.
openaire   +2 more sources

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

open access: yesAdvanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan   +16 more
wiley   +1 more source

High Dose Oestrogen in Life Threatening Obscure Gastrointestinal Bleeding

open access: yesActa Medica Indonesiana, 2022
Obscure gastrointestinal bleeding is defined as recurrent or persistent gastrointestinal bleeding in the setting of normal upper and lower endoscopies.
Meng Kang Tee   +5 more
doaj  

Massive Gastrointestinal Bleeding from Choriocarcinoma of the Ovary

open access: yesOman Medical Journal, 2018
Choriocarcinoma of the ovary is a rare neoplasm and tends to metastasize early to involve the lungs, brain, and liver. Metastasis to the gastrointestinal tract is rare.
Shiyam Kumar   +3 more
doaj   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

open access: yesAdvanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang   +10 more
wiley   +1 more source

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu   +7 more
wiley   +1 more source

Role of endoscopy in acute gastrointestinal bleeding in real clinical practice: An evidence-based review

open access: yesWorld Journal of Gastrointestinal Endoscopy, 2019
Although upper gastrointestinal bleeding is usually segregated from lower gastrointestinal bleeding, and guidelines for gastrointestinal bleeding are divided into two separate sections, they may not be distinguished from each other in clinical practice ...
K. Jung, W. Moon
semanticscholar   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

open access: yesAdvanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen   +6 more
wiley   +1 more source

Transfusion strategies for acute upper gastrointestinal bleeding.

open access: yesNew England Journal of Medicine, 2013
BACKGROUND The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy ...
C. Villanueva   +13 more
semanticscholar   +1 more source

A multicenter randomized controlled trial evaluating the effect of the use of an anti‐adhesion barrier for diverting ileostomy on the multidimensional workload in minimally invasive surgery for rectal cancer (YCOG 2005: The ADOBARRIER study)

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This multicenter, single‐blind, randomized, controlled trial was conducted to evaluate the multidimensional workload of the first operator during ileostomy closure using the SURG‐TLX between groups with and without the use of the spray‐type anti‐adhesion material during diverting ileostomy construction.
Emi Ota   +8 more
wiley   +1 more source

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