Results 51 to 60 of about 1,467,490 (296)

Cutoff CT value can identify upper gastrointestinal bleeding on postmortem CT: Development and validation study.

PLoS ONE
This study aimed to establish the diagnostic criteria for upper gastrointestinal bleeding (UGIB) using postmortem computed tomography (PMCT). This case-control study enrolled 27 consecutive patients with autopsy-proven UGIB and 170 of the 566 patients ...
Naomasa Okimoto, Masanori Ishida, Wataru Gonoi, Kotaro Fujimoto, Keisuke Nyunoya, Mariko Kurokawa, Go Shirota, Hiroyuki Abe, Tetsuo Ushiku, Osamu Abe   +9 more
doaj   +1 more source

Composition analysis of gastrointestinal contents of laboratory‐reared and wild lake sturgeon (Acipenser fulvescens)

Aquaculture, Fish and Fisheries, 2023
This study assessed the composition of digesta from captive and wild Acipenser fulvescens to consider how food availability and dietary absorption may influence stocking survival.
Afroza Naznin, Janet Genz
doaj   +1 more source

Comparison on Protein Bioaccessibility of Soymilk Gels Induced by Glucono-δ-Lactone and Lactic Acid Bacteria

Molecules, 2022
In this study, the protein bioaccessibility of soymilk gels produced by the addition of glu-cono-δ-lactone (GDL) and fermentation with lactic acid bacteria (LAB) was examined using an in vitro gastrointestinal simulated digestion model.
Tianran Hui, Ting Tang, Xuan Gu, Zhen Yuan, Guangliang Xing   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Gastrointestinal nitric oxide generation in germ-free and conventional rats

, 2004
Nitric oxide (NO) is a central mediator of various physiological events in the gastrointestinal tract. The influence of the intestinal microflora for NO production in the gut is unknown.
Sobko, T, Reinders, C, Norin, E, Midtvedt, T, Gustafsson, LE, Lundberg, JO   +5 more
core   +1 more source

Synthesis and Properties of Macrocyclic Butanoic Acid Conjugates as a Promising Delivery Formulation for the Nutrition of Colon

The Scientific World Journal, 2013
Butanoic acid plays a significant role in the maintenance of mucosal health and is the preferred energy substrate for the cells in the colon. Here, butanoic acid was selectively conjugated to the secondary hydroxyl group of β-cyclodextrin through ester ...
Jingui Cheng, Benpeng Li, Peipei Ma, Mengying Liu, Zhizhong Wang   +4 more
doaj   +1 more source

First record of microplastics in two freshwater fish species (Iheringhthys labrosus and Astyanax lacustris) from the middle section of the Uruguay River, Brazil

Acta Limnologica Brasiliensia, 2020
Aim The aim was to analyze the incidence of microplastics in the diet of fish in the middle Uruguay River. Methods The present work analyzed the gastrointestinal content of two species: Astyanax lacustris and Iheringichthys labrosus. Results This study
Tacieli dos Santos, Rodrigo Bastian, Juliana Felden, Adelita Maria Rauber, David Augusto Reynalte-Tataje, Franco Teixeira de Mello   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Nitrogen Content of Gastrointestinal Tracts of Rats During Absorptive Period.

Experimental Biology and Medicine, 1958
Summary1) The basal level of endogenously supplied nitrogen in adult rats is about 5 mg after 1 1/2 hours, and this level is unaffected by protein depletion. On feeding skim milk powder, 22–27% of the ingested protein disappeared from the gastrointestinal tract within 3 hours.
E, GEIGER, L E, HUMAN, M J, MIDDLETON
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source