Results 81 to 90 of about 1,467,490 (296)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Systematic investigation of gastrointestinal diseases in China (SILC): validation of survey methodology [PDF]

, 2009
Background: Symptom-based surveys suggest that the prevalence of gastrointestinal diseases is lower in China than in Western countries. The aim of this study was to validate a methodology for the epidemiological investigation of gastrointestinal symptoms
Zou, Duowu, Li, Q., Wang, R., Zhao Yanfang, Kang, Xiaoping, Ping Yin, Zhao, Y., Halling, Katarina, Yan Xiaoyan, Yan, H., Halling Katarina, Dent, John, Sung, Joseph, Fang Jiqian, Duowu Zou, Jia He, Yan, X., Sung Joseph, He Jia, Yan Hong, Zou Duowu, Liu Wenbin, Hao, Y., Liu, W., Joseph Sung, Yuantao Hao, Qiang Li, Katarina Halling, Ma, X., Fang, J., Yan, Xiaoyan, He, J., Xiaoping Kang, Ma Xiuqiang, Wenbin Liu, Halling, K., Yin, P., Ma, Xiuqiang, Xiuqiang Ma, Liu, Wenbin, Dent John, Yanfang Zhao, Kang, X., Johansson, S., Yin, Ping, Li Qiang, Wang Rui, Hao Yuantao, Johansson Saga, Yan, Hong, Hong Yan, Yin Ping, He, Jia, Saga Johansson, Dent, J., Xiaoyan Yan, Wang, Rui, Rui Wang, Li, Qiang, Jiqian Fang, Hao, Yuantao, John Dent, Zhao, Yanfang, Johansson, Saga, Sung, J., Kang Xiaoping, Fang, Jiqian, Zou, D.   +67 more
core   +2 more sources

Bacterial flagellin is a dominant, stable innate immune activator in the gastrointestinal contents of mice and rats. [PDF]

Gut Microbes, 2023
Vijay-Kumar M, Bovilla VR, Yeoh BS, Golonka RM, Saha P, Joe B, Gewirtz AT.   +6 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Age-Related Topographical Metabolic Signatures for the Rat Gastrointestinal Contents

, 2016
Symbiotic gut microbiota is essential for mammalian physiology and analyzing the metabolite compositions of gastrointestinal contents is vital for understanding the microbiome–host interactions.
Yuan Tian (225002), Limin Zhang (297459), Huiru Tang (115310), Yulan Wang (50197)   +3 more
core   +1 more source

Evaluation of bioaccessibility of bioactive compounds in ready-to-eat refrigerated and frozen broccoli using in vitro digestion models

Scientific Reports
Refrigerated and frozen ready-to-eat cooked vegetables are becoming increasingly popular with consumers and catering services. Simulating digestion is essential for accurately assessing the nutritional value of ready-to-eat vegetables, as raw composition
Mohamed Awad Abd Allah, Ghada Khiralla, Hesham Elhariry   +2 more
doaj   +1 more source

High Fe and Ca contents contribute to geologically-high As but bioaccessibly-low As in karstic residential soils

Soil & Environmental Health
Karstic soils are often naturally-high in As contents, primarily due to the secondary enrichment during soil weathering from carbonate rocks. However, the As risk via soil exposure for residents in karst areas remains unclear. In this study, we collected
Yuanchen Zhang, Guobing Lin, Chenjing Liu, Zhongfang Yang, Lena Q. Ma   +4 more
doaj   +1 more source

Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control

Frontiers in Endocrinology, 2018
The gastrointestinal tract stores ingested nutrients in the stomach which are then delivered to the small intestine at a controlled rate to optimize their digestion and absorption. The interaction of nutrients with the small and large intestine generates
Cong Xie, Xuyi Wang, Xuyi Wang, Richard L. Young, Richard L. Young, Michael Horowitz, Christopher K. Rayner, Tongzhi Wu, Tongzhi Wu   +8 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Therapeutic potential of Saccharomyces boulardii in alleviating gastrointestinal stress through preservation of intestinal cell membrane integrity

BMC Microbiology
Background Saccharomyces boulardii shows great promise as a treatment for osteoporosis since it plays a crucial role in protecting against inflammatory bone loss and demonstrates exceptional resilience to gastrointestinal stress during oral ...
Dingkang Wang, Chao Li, Jiabo Lai, Sha Liu, Yongjie Zhang, Zhenxin Xu, Liang Yan, Quan Wang, Yining Gong, Chongde Wu   +9 more
doaj   +1 more source