Results 121 to 130 of about 10,588,678 (413)

Tight junction proteins in gastrointestinal and liver disease

Gut, 2018
Over the past two decades a growing body of evidence has demonstrated an important role of tight junction (TJ) proteins in the physiology and disease biology of GI and liver disease.
M. Zeisel, P. Dhawan, T. Baumert
semanticscholar   +1 more source

Microbiota and gastrointestinal diseases

Anales de Pediatría (English Edition), 2015
The bacterial colonisation is established immediately after birth, through direct contact with maternal microbiota, and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation of the immune system, leading to intra- or extra-
openaire   +3 more sources

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source

Osteoporosis in Gastrointestinal Diseases

Advances in Clinical and Experimental Medicine, 2015
Secondary osteoporosis occurs as an isolated pathology or co-exists with types I and II osteoporosis. The gastroenterologist may come across osteoporosis or osteopenia in a patient with a gastrointestinal disease. This is often a young patient in whom investigations should be carried out and appropriate treatment initiated, aimed at preventing bone ...
Liliana Łykowska-Szuber, Piotr Eder, Aleksandra Szymczak, Krzysztof Linke, Iwona Krela-Kaźmierczak   +4 more
openaire   +3 more sources

Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts. [PDF]

, 2017
ObjectiveTo compare faecal microbial composition in patients with systemic sclerosis (SSc) from 2 independent cohorts with controls and to determine whether certain genera are associated with SSc-gastrointestinal tract (GIT) symptoms.DesignAdult patients
Braun, Jonathan, Chang, Lin, Chang, Yu-Ling, Clements, Philip J, Hoffmann-Vold, Anna-Maria, Hov, Johannes R, Jacobs, Jonathan P, Kummen, Martin, Labus, Jennifer S, Lagishetty, Venu, Mayer, Emeran A, Midtvedt, Øyvind, Molberg, Øyvind, Tillisch, Kirsten, Volkmann, Elizabeth R   +14 more
core   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Linking gene expression to clinical outcomes in pediatric Crohn’s disease using machine learning

Scientific Reports
Pediatric Crohn’s disease (CD) is characterized by a severe disease course with frequent complications. We sought to apply machine learning-based models to predict risk of developing future complications in pediatric CD using ileal and colonic gene ...
Kevin A. Chen, Nina C. Nishiyama, Meaghan M. Kennedy Ng, Alexandria Shumway, Chinmaya U. Joisa, Matthew R. Schaner, Grace Lian, Caroline Beasley, Lee-Ching Zhu, Surekha Bantumilli, Muneera R. Kapadia, Shawn M. Gomez, Terrence S. Furey, Shehzad Z. Sheikh   +13 more
doaj   +1 more source

Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding [PDF]

, 2019
Objective The aim of this study was to assess the efficacy and safety of intravenous ferric carboxymaltose (FCM) following hospitalization for acute gastrointestinal bleeding (AGIB) in the context of a restrictive transfusion strategy.
Ballester-Clau, Raquel, Cucala-Ramos, Mercedes, López-Barroso, Laura, Planella de Rubinat, Montse, Reñé Espinet, Josep Maria, Torres Vicente, Gisela, Voltà-Pardo, Tania   +6 more
core   +2 more sources

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Extracellular vesicle-mediated bidirectional communication between the liver and other organs: mechanistic exploration and prospects for clinical applications

Journal of Nanobiotechnology
The liver, functioning as an endocrine organ, secretes a variety of substances that influence the activities of other body organs. Conversely, molecules generated by organs such as bone, the gut, and adipose tissue can also impact liver function ...
Wenhui Mo, Yunke Peng, Yanyi Zheng, Shenglan Zhao, Liling Deng, Xiaoli Fan   +5 more
doaj   +1 more source