Results 141 to 150 of about 692,603 (317)
Gastrointestinal Disease: New Diagnostic and Therapeutic Approaches. [PDF]
Jabłońska B, Mrowiec S.
europepmc +1 more source
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue+15 more
wiley +1 more source
Pleural effusion due to nonmalignant gastrointestinal disease. [PDF]
Ferreiro L+8 more
europepmc +1 more source
Hypoxic and low‐glucose conditions in tumor tissues trigger colorectal tumor cell pyroptosis via sequential activation of the Caspase‐1/Caspase‐6/GSDMC axis. High mobility group box 1 (HMGB1), released from GSDMC‐mediated pyroptotic tumor cells, upregulates CXCL2 expression in adjacent tumor cells, thereby recruiting myeloid‐derived suppressor cells ...
Hanchao Gao+11 more
wiley +1 more source
Gastrointestinal disease in end-stage renal disease. [PDF]
Khan A+4 more
europepmc +1 more source
Association Between Migraine and Gastrointestinal Disease in Pediatric Patients: A Propensity Score Weighting Approach. [PDF]
Rhew K.
europepmc +1 more source
hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation
This article addresses the absence of zonation features in current organoid models by co‐culturing human embryonic stem cell‐derived hepatocytes with liver sinusoidal endothelial cells exhibiting distinct zonal characteristics. It demonstrates that differential WNT2 signaling from endothelial cells modulates hepatocyte zonation and metabolic functions,
Yuying Zhang+13 more
wiley +1 more source
Prescription analgesic overuse in older adults: Can we mitigate this growing problem?
With older adults already on numerous prescription medications to manage their chronic conditions, the addition of pain medications could impose an even greater burden due to dependency issues. We need to understand the use of chronic pain medication, especially opioids, discuss current strategies and gaps, and offer potential solutions to mitigate ...
Sara Kakatkar+2 more
wiley +1 more source
Special Issue: "Novel Diagnosis and Treatment of Gastrointestinal Disease". [PDF]
Georgescu D, Bratosin F.
europepmc +1 more source