Results 161 to 170 of about 10,588,678 (413)
BRD4: an effective target for organ fibrosis
Fibrosis is an excessive wound-healing response induced by repeated or chronic external stimuli to tissues, significantly impacting quality of life and primarily contributing to organ failure.
Qun Wei+8 more
doaj +1 more source
Gastrointestinal nematodes of Ovis aries in Eastern Cape, South Africa and an evaluation of current anthelmintic procedures [PDF]
Humans have known about helminth infections since ancient times. Today half of the human population is plagued by a nematode infection. Nematodes are responsible for billions of dollars in global crop damage annually and have had devastating effects on ...
Rowell, Melyssa
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Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee+9 more
wiley +1 more source
Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis+6 more
wiley +1 more source
Hyperphosphatemia and secondary hyperparathyroidism (SHPT) are the common complications found in CKD that lead to severe complications including mineral bone disease (MBD), vascular calcification (VC), and cardiovascular mortality.
Weerapat Anegkamol+9 more
doaj +1 more source
Cutaneous Manifestations in Inflammatory Bowel Diseases [PDF]
Inflammatory bowel diseases have a high frequency in Europe. They are chronic disorders that evolve with relapses and remissions. Clinical features include the signs of underlying inflammatory bowel disease and also signs of extraintestinal ...
Benea, Vasile+6 more
core +2 more sources
This study presents a multiphasic bile duct construct composed of biocompatible materials and cells, featuring an inner layer that supports biliary epithelium growth, a middle layer providing mechanical strength, and an outer cell‐permissive layer designed to support future in vivo integration.
Mattia Pasqua+9 more
wiley +1 more source
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng+7 more
wiley +1 more source
Upper Gastrointestinal Involvement in Pediatric Crohn's Disease Reply [PDF]
David C. Wilson+12 more
core +1 more source
Gastrointestinal complications of hepatic transplantation [PDF]
In this series of 150 orthotopic hepatic transplants, clinically significant gastrointestinal hemorrhage occurred in 34 patients (23%). Five patients (15%) survived this complication.
Koep, LJ, Starzl, TE, Weil, R
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