Results 271 to 280 of about 10,588,678 (413)

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen, Ji‐Jun Shan, Mo Chen, Zong Wu, Yi‐Ming Zhao, Hong‐Xu Zhu, Xin Jin, Yi‐Xiu Wang, Yi‐Bin Wu, Zhen Xiang, Zhi‐Wen Ding, Zhen‐Hai Lin, Long‐Rong Wang, Lu Wang   +13 more
wiley   +1 more source

Network Mendelian randomisation analysis deciphers protein pathways linking type 2 diabetes and gastrointestinal disease. [PDF]

Diabetes Obes Metab
Geng J, Ruan X, Wu X, Chen X, Fu T, Gill D, Burgess S, Chen J, Ludvigsson JF, Larsson SC, Li X, Du Z, Yuan S.   +12 more
europepmc   +1 more source

METABOLIC PROBLEMS ASSOCIATED WITH GASTROINTESTINAL AND PANCREATIC DISEASE

, 1984
R F McCloy
openalex   +1 more source

Energy and protein metabolism during recovery from malnutrition due to nonneoplastic gastrointestinal disease [PDF]

, 1997
Franck Carbonnel, Bernard Messing, A. Rimbert, M. Rongier, J. Koziet, Dominique Darmaun   +5 more
openalex   +1 more source

MALMPS: A Machine Learning‐Based Metabolic Gene Prognostic Signature for Stratifying Clinical Outcomes and Molecular Heterogeneity in Stage II/III Colorectal Cancer

Advanced Science, EarlyView.
Chen et al. identified a metabolic gene prognostic signature with machine‐learning framework and assessed the prognostic value in independent CRC cohorts. The metabolic signature subtypes are characterized by specific metabolic and proteomic characteristics, and associated with distinct molecular pathway and therapeutic potential.
Hao Chen, Ze Wang, Chenglong Sun, Yang Zhong, Yuan Liu, Yikun Li, Tongchao Zhang, Yuan Zhang, Xingyu Zhu, Leping Li, Feifei Teng, Ming Lu, Wei Chong   +12 more
wiley   +1 more source

Management Effects on Gastrointestinal Disease in Red Wolves (Canis rufus) Under Human Care: A Retrospective Study. [PDF]

Animals (Basel)
Fontaine AC, Campbell J, Opperman L, Minter LJ, Wolf K, Anderson KM, Kendall CJ, Lynch EC.   +7 more
europepmc   +1 more source

Recent progress in diagnosis and treatment of gastrointestinal diseases. Enteral nutrition.

, 1988
Tsuneo Takahashi
openalex   +2 more sources

Circulating antibodies to Saccharomyces cerevisiae (bakers'/brewers' yeast) in gastrointestinal disease [PDF]

, 1999
C. J. Darroch, R.M.R. Barnes, JK Dawson
openalex   +1 more source

Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening

Advanced Science, EarlyView.
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin, Joungpyo Lim, Seewoo Kim, Sangeun Lee, Wei Wen Su, Jinho Yoon, Jeong‐Woo Choi   +6 more
wiley   +1 more source

Ferroptosis: Biology and Role in Gastrointestinal Disease. [PDF]

Gastroenterology
Escuder-Rodríguez JJ, Liang D, Jiang X, Sinicrope FA.   +3 more
europepmc   +1 more source