Results 31 to 40 of about 1,253,420 (339)

Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]

, 2019
Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R., Ismagilov, Rustem F., Rolando, Justin C.   +2 more
core   +1 more source

Hepatitis C virus related cirrhosis decreased as indication to liver transplantation since the introduction of direct-acting antivirals: A single-center study [PDF]

, 2018
AIM: To evaluate waiting list (WL) registration and liver transplantation (LT) rates in patients with hepatitis C virus (HCV)-related cirrhosis since the introduction of direct-acting antivirals (DAAs).
Angeli, Paolo, Burra, Patrizia, Cillo, Umberto, Ferrarese, Alberto, Gambato, Martina, Germani, Giacomo, Russo, Francesco Paolo, Senzolo, Marco, Shalaby, Sarah, Zanetto, Alberto, Zanus, Giacomo   +10 more
core   +1 more source

Correlation between endoscopic and histopathological findings in patients with stomach lesion referred to Firoozgar Hospital, Tehran (2016-2017)

The Journal of Qazvin University of Medical Sciences, 2018
Background: Stomach is a common location for benign and malignant lesions in the digestive system from inflammation to cancer. Therefore, recognition and diagnosis in the endoscopic stage and its confirmation in a pathological examination will be ...
Golmehr Taheri, Gholam Reza Hemmasi
doaj   +1 more source

Exposure to silica and systemic sclerosis: A retrospective cohort study based on the Canadian Scleroderma Research Group

Frontiers in Medicine, 2022
IntroductionSystemic sclerosis (SSc) is thought to be induced by an environmental trigger in genetically predisposed individuals. This study assessed the demographic and clinical characteristics and disease severity of silica exposed SSc patients ...
Anastasiya Muntyanu, Raymond Milan, Raymond Milan, Elham Rahme, Elham Rahme, Avery LaChance, Lydia Ouchene, Maxime Cormier, Ivan V. Litvinov, Ivan V. Litvinov, Marie Hudson, Marie Hudson, Murray Baron, Elena Netchiporouk, the Canadian Scleroderma Research Group, M. Baron, M. Hudson, G. Gyger, J. Pope, M. Larche, N. Khalidi, A. Masetto, E. Sutton, T. S. Rodriguez Reyna, N. Maltez, C. Thorne, P. R. Fortin, A. Ikic, D. Robinson, N. Jones, S. LeClercq, P. Docherty, D. Smith, M. J. Fritzler   +33 more
doaj   +1 more source

Endocannabinoid-related compounds in gastrointestinal diseases [PDF]

, 2018
The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functions at both peripheral and central levels.
Alessandra, D'Alessandro, Esposito, Giuseppe, Gigli, Stefano, Giovanni, Sarnelli, Marcella, Pesce, Osvaldo, Borrelli, Rosario, Cuomo, Seguella, Luisa   +7 more
core   +1 more source

Comparison of CD4+ and CD8+ T- lymphocyte in Helicobacter pylori-negative functional dyspepsia

Caspian Journal of Internal Medicine, 2020
Background: Functional dyspepsia (FD) is the most common gastrointestinal disorder with several symptoms such as stomach pain and abdominal bloating. The aim of this study was to investigate and compare CD4+ and CD8+ in the Helicobacter pylori-negative ...
Leila Vahedi, Sousan Mirnajd Gerami, Kourosh Masnadi-Shirazi, Seyed Kazem Mirinezhad, Shabnam Salehi, Monireh Halimi   +5 more
doaj  

Potential Role for Combined Subtype-Selective Targeting of M1 and M3 Muscarinic Receptors in Gastrointestinal and Liver Diseases

Frontiers in Pharmacology, 2021
Despite structural similarity, the five subtypes comprising the cholinergic muscarinic family of G protein-coupled receptors regulate remarkably diverse biological functions.
Mazen Tolaymat, Margaret H. Sundel, Madeline Alizadeh, Guofeng Xie, Guofeng Xie, Guofeng Xie, Jean-Pierre Raufman, Jean-Pierre Raufman, Jean-Pierre Raufman, Jean-Pierre Raufman   +9 more
doaj   +1 more source

A Case of Strangulated Intestinal Obstruction Caused by Acquired Ileal Diverticulum

Case Reports in Gastrointestinal Medicine
Conclusion: Acquired ileal diverticulum leading to strangulated intestinal obstruction is rare. Clinicians should consider the possibility of this disease when encountering intestinal obstruction patients with no history of abdominal surgery.
Zhong-Yu Wang, Zhe Han, Hong-Fei Pang, Yu-Hang Liu, Ming Wei, Yuan-Yuan Wang   +5 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Mortality risk of patients with intestinal obstruction

BMC Cancer
Background Intestinal obstruction represents a severe intestinal disease associated with higher mortality rates. However, the determinants of mortality in patients with intestinal obstruction remain inadequately understood. This study sought to elucidate
Yuanyuan Wang, Wei Li, Chuan-min Zhou, Zifeng Zhao, Jianwei Ma, Haibo Jiang, Ming Wei, Yingchao Gao, Yongjun Dai, Xing Zhang, Ning Yang, Feng Feng, Jian Zhang, Yiding Ji, Jianjie Liu, Chao Zhang, Like Li, Xia Jiang, Zhongxin Li, Zengren Zhao   +19 more
doaj   +1 more source