Results 71 to 80 of about 1,253,420 (339)

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Pyloric leiomyoma: behavioural aspects in a shelter dog [PDF]

Macedonian Veterinary Review, 2015
The present report describes a case of pyloric wall leiomyoma in a shelter dog with a history of vomiting, pica, licking and chewing the walls of the kennel. The clinical, radiological, ultrasound, hematological and blood chemistry examinations showed no
Riccardo Benedetti, Mirko Barabucci, Alessandra Pigliapoco, Simona Cannas, Clara Palestrini   +4 more
doaj   +1 more source

Quality of life and chronic pain four years after gastrointestinal surgery [PDF]

, 2006
PURPOSE: Little is known about the prevalence of chronic postsurgical pain after gastrointestinal surgery. This study was designed to assess the prevalence of chronic pain and quality of life in a cohort of patients who underwent surgery for benign and ...
Bruce, Julie, Krukowski, Zygmunt H.
core   +1 more source

AKR1B10 in gastrointestinal diseases

Aging, 2015
Ulcerative colitis (UC) is characterized by long-standing mucosal inflammation of the large bowel, with increased tendency of developing colorectal cancer (CRC), i.e., colitis-associated cancer (CAC) [1]. The other two predisposing conditions for CRC are familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC), whose ...
Duan-Fang Liao, Yi Shen, Deliang Cao, Deliang Cao   +3 more
openaire   +3 more sources

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Physical activity and elevated liver enzymes: A cross-sectional study from the PERSIAN Guilan cohort study [PDF]

Caspian Journal of Internal Medicine
Background: Regular physical activity promotes health that can affect liver health, particularly modulating liver enzymes. The objective of this study was to assess the association between physical activities and elevated liver enzyme levels in the ...
Heydar Ali Balou, Farahnaz Joukar, Milad Shahdkar, Mahdi Orang Goorabzarmakhi, Saman Maroufizadeh, Fariborz Mansour-Ghanaei   +5 more
doaj  

The global stress response regulator oxyS in an adherent-invasive Escherichia coli strain attenuates experimental colitis

Gut Microbes
Crohn’s disease and ulcerative colitis in humans and experimental immune-mediated colitis in mice are likely due in part to overactive immune responses to resident intestinal bacteria, including certain strains of adherent-invasive Escherichia coli (E ...
Diana Arsene, Sandrine Y. Tchaptchet, Jonathan J. Hansen   +2 more
doaj   +1 more source

Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systems. [PDF]

, 2013
Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), graft-versus-host disease (GVHD), and inflammatory bowel diseases such as ulcerative colitis and Crohn's disease are common human gastrointestinal diseases that share inflammation as a key
Bortner, James D, Falk, Gary W, Hartman, Kira G, Lynch, John P, Martín, Martín G, Rustgi, Anil K, Yu, Jian   +6 more
core   +2 more sources

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Different behaviour of BK-virus infection in liver transplant recipients [PDF]

, 2016
Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola, Muiesan, Paolo, TINTI, FRANCESCA, UMBRO, ILARIA   +3 more
core   +3 more sources