Results 81 to 90 of about 10,588,678 (413)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Association between water source and chronic gastrointestinal diseases in Chinese: A cross-sectional and longitudinal study

Frontiers in Public Health, 2022
BackgroundGastrointestinal health is closely associated with the quality of the water supply. However, long-term associations between the water supply type and chronic gastrointestinal disease (CGD) are unclear.MethodThe water supply was categorized as ...
Hehua Zhang, Yang Xia, Qing Chang, Xiangsu Zhang, Yuhong Zhao, Yuhong Zhao   +5 more
doaj   +1 more source

Long-term gastrointestinal outcomes of COVID-19

Nature Communications, 2023
A comprehensive evaluation of the risks and 1-year burdens of gastrointestinal disorders in the post-acute phase of COVID-19 is needed but is not yet available.
Evan Xu, Yan Xie, Z. Al-Aly
semanticscholar   +1 more source

Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine [PDF]

, 2019
Background: The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake.
Bogatyrev, Said R., Ismagilov, Rustem F., Rolando, Justin C.   +2 more
core   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Exploring the Association between Elevated Liver Enzymes and Diabetes in the PERSIAN Guilan Cohort Study [PDF]

Caspian Journal of Internal Medicine
Background: Diabetes mellitus (DM) is highly consequential to global health among chronic diseases. Due to a limited researches that have examined relationships between liver enzymes and DM, this study aimed to investigate the link between elevated liver
Mohammad Taghi Ashoobi, Farahnaz Joukar, Kourosh Mojtahedi, Saman Maroufizadeh, Mohammadreza Javid, Ali Parvaneh, Tahereh Zeinali, Niloofar Faraji, Mohammadreza Naghipour, Fariborz Mansour-Ghanaei   +9 more
doaj  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Changes in malaria epidemiology in Germany, 2001–2016: a time series analysis

Malaria Journal, 2018
Background German surveillance data showed a sharp rise of malaria cases in 2014 and 2015 due to the increased arrival of refugees from malaria endemic countries.
Sabine Vygen-Bonnet, Klaus Stark
doaj   +1 more source

Evaluating Disease Patterns of Military Working Dogs in the Republic of Korea: A Retrospective Study

Animals, 2023
The purpose of this study was to evaluate disease patterns among military working dogs (MWDs) at the Armed Forces Medical Research Institute (AFMRI) to provide basic medical data on Korean MWDs.
Sanghyeon Park, Gyeonggook Park, Mi-Sun Rieu, Taewoo Kim, Dongwook Kim, Sungin Lee, Gonhyung Kim   +6 more
doaj   +1 more source

Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease

Nutrients, 2019
Fermented foods are defined as foods or beverages produced through controlled microbial growth, and the conversion of food components through enzymatic action.
E. Dimidi, S. Cox, M. Rossi, K. Whelan
semanticscholar   +1 more source