Results 101 to 110 of about 10,601,238 (387)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Association between Gastrointestinal Diseases and Migraine [PDF]

, 2022
Jemin Kim, Sujin Lee, Kiyon Rhew
openalex   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Recurrent Gastrointestinal Bleeding in a Man with Osler-Weber-Rendu Syndrome and Intestinal Varices

Canadian Journal of Gastroenterology, 1988
A patient with Osler-Weber-Rendu disease and idiopathic intestinal varices who presented with recurrent gastrointestinal hemorrhage and iron deficiency anemia is reported. The unique coexistence of these two rare disorders is discussed and the literature
Robert N. Clark, William G. Paterson, Laurington R. DaCosta, Ivan T. Beck   +3 more
doaj   +1 more source

An evaluation of 605 endoscopic examination in a rural setting, Lacor Hospital in Northern Uganda [PDF]

, 2016
Introduction: The aim of this study was to evaluate the profile of esophagogastroduodenal (EGDS) diseases diagnosed by upper endoscopy in a rural area of Uganda in a retro-protective study of 605 patients.
Alema NO, Ogwang DM, Okello TR, Pecorella I.   +3 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Rectal bleeding as a symptom of solitary rectal ulcer syndrome mimicking rectal neoplasm on colonoscopy: A case report

Clinical Case Reports, 2023
Key Clinical Message Patients complaining of rectal bleeding, constipation, and a suspicious mass in colonoscopy should undergo biopsy. Histological features such as fibromuscular obliteration in the lamina propria favor SRUS, a benign disorder.
Masood Faghih Dinevari, Amirtaher Eftekharsadat, Mahdi Tarverdizadeh, Seyyed Mahdi Rasulimanesh, Ali Riazi, Amirreza Jabbaripour Sarmadian, Samaneh Abbasian   +6 more
doaj   +1 more source

Mucosal Adhesive Chitosan Nanogel Formulations of Antibiotics and Adjuvants (Terpenoids, Flavonoids, etc.) and Their Potential for the Treatment of Infectious Diseases of the Gastrointestinal Tract [PDF]

, 2023
Igor D. Zlotnikov, Natalya G. Belogurova, I V Poddubnaya, Еlena V. Kudryashova   +3 more
openalex   +1 more source

Design of wireless swallowable capsule with minimum power consumption and high resolution images [PDF]

, 2015
Medical technology has undergone major breakthroughs in recent years, especially in the area of the examination tools for diagnostic purposes. The traditional examination method for the diagnosis of gastrointestinal diseases is gastroscopy with the use ...
Intzes, I, Meng, H, Vassios, V
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source