Results 181 to 190 of about 837,691 (363)

Divide and Conquer: Grounding a Bleeding Areas in Gastrointestinal Image with Two-Stage Model [PDF]

open access: yesarXiv
Accurate detection and segmentation of gastrointestinal bleeding are critical for diagnosing diseases such as peptic ulcers and colorectal cancer. This study proposes a two-stage framework that decouples classification and grounding to address the inherent challenges posed by traditional Multi-Task Learning models, which jointly optimizes ...
arxiv  

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

open access: yesAdvanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap   +10 more
wiley   +1 more source

Density of States and Binding Energy Informatics for Exploring Early Disease Detection in MOF‐Metal Oxide Chemiresistive Sensors

open access: yesAdvanced Theory and Simulations, EarlyView.
Binding energy and electronic structure calculations are used to assess the ability of metal–organic framework (MOF)‐TiO2 composite materials to detect volatile organic compounds found in human breath. Electronic structure changes are measured by comparing density of states profiles using Wasserstein distances.
Maryam Nurhuda   +3 more
wiley   +1 more source

Gut microbiota and childhood malnutrition: Understanding the link and exploring therapeutic interventions

open access: yesEngineering in Life Sciences
Childhood malnutrition is a metabolic condition that affects the physical and mental well‐being of children and leads to resultant disorders in maturity.
Sevda Zoghi   +5 more
doaj   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

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