Results 261 to 270 of about 10,687,454 (378)

Mechanisms of NLRP3 inflammasome in pathogenesis and progression of inflammation-related gastrointestinal diseases. [PDF]

PeerJ
Liu F, Shao B, Zhu Y, Xue X, Wu X.
europepmc   +1 more source

The Structural Analysis of Medicinal Plants and Their Use to Treat the Gastrointestinal Tract Diseases

, 2020
Liubov Makhovska, Victoria Gniezdilova, Oksana Nespliak, Vira Buniak   +3 more
openalex   +2 more sources

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

Nanostructural insights into Mongolian medicine Harigabri and its therapeutic efficacy for gastrointestinal diseases. [PDF]

Food Chem X
Ang G, Ren Q, Ai J, Aodeng G.
europepmc   +1 more source

Gastrointestinal Permeability and Motility in Inflammatory Bowel Disease

, 2019
Anas Al-Saffar
openalex   +1 more source

Unravelling the mechanisms behind the persistent gastrointestinal symptoms in celiac disease – how can they lead to better treatment outcomes? [PDF]

, 2017
Pilvi Laurikka, Katri Kaukinen, Kalle Kurppa   +2 more
openalex   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Ferroptosis in Gastrointestinal Diseases: A New Frontier in Pathogenesis and Therapy. [PDF]

J Clin Med
Wawrzeńczyk A, Napiórkowska-Baran K, Alska E, Gruszka-Koselska A, Szynkiewicz E, Sławatycki J, Klemenska P, Bartuzi Z.   +7 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Intestinal microbiota and the efficacy of fecal microbiota transplantation in gastrointestinal disease.

, 2014
Olga C. Aroniadis, Lawrence J. Brandt
openalex   +1 more source