Results 301 to 310 of about 950,654 (339)

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

Gut microbiota in gastrointestinal diseases: Insights and therapeutic strategies. [PDF]

World J Gastroenterol
Jiang L, Fan JG.
europepmc   +1 more source

Utilizing Causal Network Markers to Identify Tipping Points ahead of Critical Transition

Advanced Science, EarlyView.
The study proposes a causal network markers (CNMs) framework to identify early‐warning signals preceding critical transitions. It validates CNMs on various computational benchmark models and real‐world datasets, demonstrating higher accuracy and flexibility compared to existing approaches.
Shirui Bian, Zezhou Wang, Siyang Leng, Wei Lin, Jifan Shi   +4 more
wiley   +1 more source

Co-Occurrence of <i>Helicobacter pylori</i> and <i>Candida</i> spp. Infections in the Pathogenesis of Gastrointestinal Diseases. [PDF]

Biomedicines
Braksator J, Kofla-Dłubacz A, Antosz-Popiołek K, Szyller H, Koga-Batko J, Wrześniewska M, Dyda M, Pytrus T.   +7 more
europepmc   +1 more source

Deciphering microbial and metabolic influences in gastrointestinal diseases-unveiling their roles in gastric cancer, colorectal cancer, and inflammatory bowel disease. [PDF]

J Transl Med
Philip D, Hodgkiss R, Radhakrishnan SK, Sinha A, Acharjee A.   +4 more
europepmc   +1 more source

A genome-wide cross-trait analysis characterizes the shared genetic architecture between lung and gastrointestinal diseases. [PDF]

Nat Commun
You D, Wu Y, Lu M, Shao F, Tang Y, Liu S, Liu L, Zhou Z, Zhang R, Shen S, Lange T, Xu H, Ma H, Yin Y, Shen H, Chen F, Christiani DC, Jin G, Zhao Y.   +18 more
europepmc   +1 more source

Mood instability and risk of gastrointestinal diseases - a univariable and multivariable mendelian randomization study. [PDF]

Ann Gen Psychiatry
Liu RL, Song QC, Liu LM, Yang YF, Zhu WH.   +4 more
europepmc   +1 more source

Correction: The effects of gut microbiome manipulation on glycemic indices in patients with non-alcoholic fatty liver disease: a comprehensive umbrella review

Nutrition & Diabetes
Azin Vakilpour, Ehsan Amini-Salehi, Arman Soltani Moghadam, Mohammad-Hossein Keivanlou, Negin Letafatkar, Arman Habibi, Mohammad Hashemi, Narges Eslami, Reza Zare, Naeim Norouzi, Hamed Delam, Farahnaz Joukar, Fariborz Mansour-Ghanaei, Soheil Hassanipour, Sandeep Samethadka Nayak   +14 more
doaj   +1 more source

Segmental overlap is common in eosinophilic gastrointestinal diseases and impacts clinical presentation and treatment. [PDF]

Dis Esophagus
Ketchem CJ, Jensen ET, Dai X, Anderson C, Kodroff E, Strobel MJ, Zicarelli A, Gray S, Cordell A, Hiremath G, Dellon ES.   +10 more
europepmc   +1 more source