Results 131 to 140 of about 770,027 (273)

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

The Gut Microbiome in Enteric Viral Infections: Underlying Mechanisms and Therapeutic Approaches

Microorganisms
Despite growing recognition of the role of the gut microbiome in host health and in modulating pathogen activity, the dynamic and reciprocal relationship between enteric viruses and the gut microbial ecosystem remains insufficiently defined and requires ...
Alejandro Borrego-Ruiz, Juan J. Borrego
doaj   +1 more source

The Influence of Omega‐3 Fatty Acids and Probiotics on Hippocampal Inflammation and Glial Cells in a Chronic Anorexia Nervosa Rat Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with brain volume reduction, glial cell loss, microbiome alterations, and dysregulated pro‐inflammatory mechanisms. However, the underlying cellular mechanisms remain inadequately elucidated, and interventions addressing these alterations are lacking.
A. C. Thelen, N. Andreani, N. M. Korten, M. Neumann, V. Verspohl, M. van Egmond, L. Kneisel, C. Voelz, L. Blischke, J. F. Baines, J. Baier, J. Schumacher, F. Kiessling, B. Herpertz‐Dahlmann, C. Beyer, L. Keller, J. Seitz, S. Trinh   +17 more
wiley   +1 more source

Gut microbiota therapy in gastrointestinal diseases

Frontiers in Cell and Developmental Biology
The human gut microbiota, consisting of trillions of microorganisms, plays a crucial role in gastrointestinal (GI) health and disease. Dysbiosis, an imbalance in microbial composition, has been linked to a range of GI disorders, including inflammatory ...
Hanif Ullah, Safia Arbab, Chengting Chang, Saira Bibi, Nehaz Muhammad, Sajid Ur Rehman, Suleman, Suleman, Irfan Ullah, Inam Ul Hassan, Yali Tian, Ka Li   +11 more
doaj   +1 more source

Maternal and neonatal microbiome diversity and metabolic pathways are modified by a gastrointestinal nematode in pregnant and lactating mice

, 2020
Manjurul Haque
openalex   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Mechanisms of intestinal dysbiosis: new insights into tuft cell functions

Gut Microbes
Symbiosis between the host and intestinal microbial communities is essential for human health. Disruption in this symbiosis is linked to gastrointestinal diseases, including inflammatory bowel diseases, as well as extra-gastrointestinal diseases ...
Nathalie Coutry, Imène Gasmi, Fabien Herbert, Philippe Jay   +3 more
doaj   +1 more source

The Microbiome in Functional Gastrointestinal Disorders Is Characterized by Bacteria and Genes Involved in Carbohydrate and Bile Acid Metabolism (OR23-01-19)

, 2019
Wayne Young, Caterina Carco, Jane Mullaney, Paul Maclean, Paul D. Cotter, Karl Fraser, Warren C. McNabb, Richard B. Gearry, Nicole C. Roy   +8 more
openalex   +1 more source

The role of the microbiome in drug resistance in gastrointestinal cancers [PDF]

, 2020
Ingrid Garajová, Rita Balsano, Heling Wang, Francesco Leonardi, Elisa Giovannetti, Dongmei Deng, Godefridus J. Peters   +6 more
openalex   +1 more source

The Link Between Gastrointestinal Microbiome And Ocular Disorders - A Review [PDF]

, 2022
Rashed Alfuzaie
openalex   +1 more source