Results 161 to 170 of about 915,734 (298)

Polyphenols as Modulators of Gastrointestinal Motility: Mechanistic Insights from Multi-Model Studies. [PDF]

Pharmaceuticals (Basel)
Chomentowski A, Drygalski K, Kleszczewski T, Berczyńska M, Tylicka M, Kapała J, Raciborska A, Zubrzycki P, Hady HR, Modzelewska B.   +9 more
europepmc   +1 more source

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

<i>Cannabis sativa</i> L. roots extract modulates gastrointestinal motility and ameliorates ethanol-induced gastric ulcers in animal models. [PDF]

Front Pharmacol
de Sá PGS, Rocha JGS, Silva JMDS, de Souza NAC, Araújo TCL, Santos VLDA, Menezes PMN, Palheta Junior RC, Silva FS, Rolim LA.   +9 more
europepmc   +1 more source

The Impact of Nutritional Therapy on Gastrointestinal Motility in Older Adults. [PDF]

Healthcare (Basel), 2023
Okawa Y.
europepmc   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

Advanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto, Emily Tsang, Marie Karen Tracy Hong Lin, Luca Mannino, Kurt V. Gothelf, Anja Boisen   +5 more
wiley   +1 more source

Correction: Epidural Co-Administration of Dexmedetomidine and Levobupivacaine Improves the Gastrointestinal Motility Function after Colonic Resection in Comparison to Co-Administration of Morphine and Levobupivacaine. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

The Effect of Dexmedetomidine Sedation on Lower Gastrointestinal Motility in Children-Is It Suitable for Anorectal Manometry? [PDF]

J Clin Med, 2023
Berger TD, Lukovits K, Cavanaugh D, Nurko S, Mason K.   +4 more
europepmc   +1 more source

Real‐Time Investigation of Interfacial Evolution in Electrochemical Energy Storage Systems via EQCM

Advanced Science, EarlyView.
Understanding the electrode/electrolyte interface (EEI) is crucial for supercapacitors and batteries. EQCM, by enabling real‐time monitoring of mass changes during charge–discharge cycles, has evolved into a vital method for analysis of EEI. It provides important insights into charge‐storage mechanisms, electrode structural evolution, ion‐transfer ...
Zixuan Wang, Situo Cheng, Guang Feng
wiley   +1 more source

Correction: Expression of Concern: Epidural co-administration of Dexmedetomidine and Levobupivacaine improves the Gastrointestinal motility function after colonic resection in comparison to co-administration of Morphine and Levobupivacaine. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source