Results 301 to 310 of about 852,425 (386)

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

Advanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu, Huitong Ruan, Xiaolin Zhang, Weihan Zheng, Muhetaierjiang Mutailifu, Ling Wang, Liu Yu, Ruijun Peng, Rui Zhao, Zihan Wang, Jie Xu, Shaochuan Li, Yaobin Wu, Wenguo Cui, Mujun Lu   +14 more
wiley   +1 more source

Zuojin Pill enhances gastrointestinal motility by modulating the pacemaker potentials in interstitial cells of Cajal through multiple signaling pathways. [PDF]

Int J Med Sci
Lee J, Ko SJ, Choi NR, Choi WG, Seo M, Koo SH, Jung D, Lee MJ, Lee JH, Park JW, Kim BJ.   +10 more
europepmc   +1 more source

Advancing Soil Organic Carbon Prediction: A Comprehensive Review of Technologies, AI, Process‐Based and Hybrid Modelling Approaches

Advanced Science, EarlyView.
This review highlights advances in soil organic carbon (SOC) quantification using remote sensing, proximal soil sensing, AI (ML and DL), and biogeochemical modelling. Integrating diverse data sources and models improves SOC prediction accuracy. Key priorities include enhancing data availability, refining models, incorporating microbial processes, and ...
Zijuan Ding, Ke Liu, Sabine Grunwald, Pete Smith, Philippe Ciais, Bin Wang, Alexandre M.J.‐C. Wadoux, Carla Ferreira, Senani Karunaratne, Narasinha Shurpali, Xiaogang Yin, Dale Roberts, Oli Madgett, Sam Duncan, Meixue Zhou, Zhangyong Liu, Matthew Tom Harrison   +16 more
wiley   +1 more source

Antispasmodic Activity of Light-Roasted Coffee Extract and Its Potential Use in Gastrointestinal Motility Disorders. [PDF]

Foods
Duangjai A, Rawangkan A, Yosboonruang A, Ontawong A, Saokaew S, Goh BH, Suganuma M, Phisalprapa P.   +7 more
europepmc   +1 more source

Probiotic‐Enhanced Porous Bio‐Hybrids with Inflammatory Targeting, ROS Scavenging, and Long‐Term Drug Release for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
Probiotic‐enhanced porous bio‐hybrids (E‐xPAM@ASA), developed by coupling the drug‐loaded hairy microporous nanospheres xPAM@ASA with probiotic EcN, integrate inflammatory‐targeting, ROS scavenging, and long‐term release of 5‐ASA to improve inflammation and regulate microbiota structure in the DSS‐induced colitis model, providing an advanced strategy ...
Luna Quan, Yang Ouyang, Weiwen Liang, Zixin Chen, Dongtian Miao, Bingna Zheng, Dingcai Wu, Rongkang Huang   +7 more
wiley   +1 more source

Insights into the current state of knowledge, practice, and attitudes of physicians regarding gastrointestinal motility disorders in Egypt. [PDF]

BMC Gastroenterol
Al Mowafy EA, AboKresha MM, Elkhadry SW, Hashem MB, Elganzory A, Sayed SA, Khaskia MA.   +6 more
europepmc   +1 more source

Proximal gastrointestinal and gallbladder motility after colectomy with pouch reconstruction

, 2000
J.-M. Steens, U.G. Schlueter, M. K. Vu, Willem A. Bemelman, G. Griffioen, R. A. van Hogezand, C. B. H. W. Lamers, Ad Masclee   +7 more
openalex   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

Advanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen, Qing Zhang, Jiajia Li, Xia Zhou, Daxing Gao, Lu Li, Dabing Huang, Jizhou Wang, Zhutian Zeng   +8 more
wiley   +1 more source

Contractile mechanism of GM-611 on gastrointestinal motility in conscious dogs

, 2000
Hirokazu Sudo, Kenichi Ozaki, Mitsu Onoma, Kenshi Kamei, Takashi Dan, Hisanori Takanashi, Zen Itoh, Satoshi Ōmura   +7 more
openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source