Results 331 to 340 of about 852,425 (386)

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

open access: yesAdvanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim   +7 more
wiley   +1 more source

Edible and Recyclable Gelatin‐Based Electronics for High‐Precision Health and Environmental Monitoring

open access: yesAdvanced Science, EarlyView.
An edible and recyclable composite film composed of gelatin and activated charcoal is presented for multifunctional health and environmental monitoring. The edible films exhibit tuneable mechanical and electrical properties, along with multimodal sensing capabilities for strain, humidity, and temperature. The composite film is degradable and recyclable,
Ming Dong   +6 more
wiley   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Structural Basis of GABAB Receptor Activation during Evolution

open access: yesAdvanced Science, EarlyView.
This study explores the structural and functional mechanisms of the drosophila GABAB receptor, a key role in neurotransmission. Using cryo‐EM, the research reveals how the receptor's activation differs from its human counterpart, highlighting unique evolutionary features.
Guofei Hou   +14 more
wiley   +1 more source

All Organic Fully Integrated Neuromorphic Crossbar Array

open access: yesAdvanced Electronic Materials, EarlyView.
In this work, the first fully integrated crossbar array of electrochemical random‐access memory (ECRAM) that is composed entirely of organic materials is represented. This array can perform inference and in situ parallel training and is capable of classifying linearly separable 2D and 3D classification tasks with high accuracy.
Setareh Kazemzadeh   +2 more
wiley   +1 more source

Charge Injection and Transport in an Isoindigo‐Based Polymer Transistor

open access: yesAdvanced Electronic Materials, EarlyView.
This study presents the charge injection and transport properties of field‐effect transistors based on an isoindigo‐bithiophene donor‐acceptor polymer semiconductor contacted with thiolated self‐assembled monolayer (SAM)‐functionalized electrodes. Temperature‐dependent contact characteristics are measured and simulated.
Zuchong Yang   +8 more
wiley   +1 more source

Foreign labor, peer‐networking and agricultural efficiency in the Italian dairy sector

open access: yesAgribusiness, EarlyView.
Abstract While the presence of immigrants in the agricultural sector is widely acknowledged, the empirical evidence on its economic consequences is lacking, especially from a microeconomic perspective. Using the Farm Accountancy Data Network panel data for Italian dairy farms in the period 2008–2018, the present study investigates the relationship ...
Federico Antonioli   +2 more
wiley   +1 more source

Wine Tourism as a Catalyst for Sustainable Performance: The Mediating Role of Corporate Legitimacy and Green Innovation

open access: yesAgribusiness, EarlyView.
ABSTRACT This study aims to explore the influence of Wine Tourism (WT) on the Sustainable Performance (SP) of wineries in Spain. It particularly investigates how Corporate Social Legitimacy (CSL) and Green Innovation (GI) may act as intermediary factors in this relationship.
Javier Martínez‐Falcó   +3 more
wiley   +1 more source

Current status of intestinal transplantation. [PDF]

open access: yes, 1994
Abu-Elmagd, K   +4 more
core  

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