Results 221 to 230 of about 63,208 (240)
Some of the next articles are maybe not open access.
Gastrointestinal stromal tumors
Abdominal Imaging, 2006We reviewed radiologic features of gastrointestinal stromal tumors (GISTs) and correlated them with clinical and pathologic findings.We investigated a series of 39 c-Kit-positive GISTs. Clinical and radiologic findings and management of these patients were recorded.Twenty women and 19 men (mean age 64 years) had histologically proved GIST.
A, Darnell +8 more
openaire +4 more sources
Gastrointestinal stromal tumors
Virchows Archiv, 2010Gastrointestinal stromal tumors (GISTs) have emerged from being poorly defined, treatment-resistant tumors to a well-recognized, well-understood, and treatable tumor entity within only one decade. The understanding of GIST biology has made this tumor a paradigm for molecularly targeted therapy in solid tumors and provides informative insights into the ...
Bernadette, Liegl-Atzwanger +2 more
openaire +2 more sources
Gastrointestinal stromal tumor
Surgical Oncology, 2008Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. These form a distinct category of tumors characterized by oncogenic mutations of the KIT receptor tyrosine kinase in a majority of patients. KIT is used not only for diagnosis but also for targeted therapy of GISTs.
Puneet, Gupta +2 more
openaire +2 more sources
Gastrointestinal Stromal Tumors
Hematology/Oncology Clinics of North America, 2005Gastrointestinal stromal tumors (GISTs) are identified pathologically by the expression of KIT. The management of GISTs has been altered significantly by the development of imatinib mesylate, a tyrosine kinase inhibitor with activity against KIT and platelet-derived growth factor receptors.
Margaret, von Mehren, James C, Watson
openaire +2 more sources
RETROVESICAL GASTROINTESTINAL STROMAL TUMOR
Journal of Urology, 2001Primitive mesenchymal gastrointestinal tumors without evidence of differentiation are referred to as gastrointestinal stromal tumors. Because gastrointestinal stromal tumors are known for their wide variability in clinical behavior and for the difficulty in determining their malignant potential, numerous studies have been done to define better useful ...
Y S, Lee +3 more
openaire +2 more sources
GASTROINTESTINAL STROMAL TUMOR
2010Gastrointestinal stromal tumor, i.e., GIST is by far the most common mesenchymal tumor of the gastrointestinal tract. GIST has received special clinical attention, because it is one of the first solid tumors treated with tyrosine kinase inhibitors as targeted oncological therapy.
openaire +2 more sources
Pediatric gastrointestinal stromal tumor
Seminars in Pediatric Surgery, 2012Pediatric gastrointestinal stromal tumor (GIST) is a rare entity that can be quite different from its adult counterpart. This report provides a comprehensive review on the diagnosis and management of this tumor in children and adolescents, including its oncogenesis and associated syndromes.
Katherine A, Janeway +1 more
openaire +2 more sources
Pediatric Gastrointestinal Stromal Tumors
Hematology/Oncology Clinics of North America, 2009Gastrointestinal stromal tumors (GISTs) rarely occur in pediatric patients, but increased recognition of adult GIST has led to better awareness of the existence of this entity in the pediatric population. GIST occurring in pediatric patients has a unique biology and clinical behavior and warrants discussion as an independent entity.
Alberto S, Pappo, Katherine A, Janeway
openaire +2 more sources
Gastrointestinal stromal tumors (GISTs)
Current Opinion in Gastroenterology, 2004Gastrointestinal stromal tumors (GISTs) have recently been the subject of considerable clinical and experimental interest. This focus is based on the recognition that GISTs characteristically have uncontrolled activation of the KIT protein, a transmembrane tyrosine kinase receptor involved in cell survival, development, and proliferation.
Mandeep S, Saund +2 more
openaire +2 more sources
Gastrointestinal stromal tumors
Current Treatment Options in Oncology, 2000The nonepithelial, nonlymphoid tumors of the gastrointestinal tract are heterogeneous in terms of clinical presentation, behavior, pathology, and genetic features. Concepts regarding these tumors have changed rapidly over the past decade as nomenclature has evolved. Many of these tumors have no muscle differentiation, and designations such as leiomyoma
openaire +2 more sources