Results 131 to 140 of about 2,259,874 (301)

Gastrointestinal manifestations of COVID-19 in women with endometriosis: a prospective observational cohort study

Gastroenterologìa
Background. Women with endometriosis may be at increased risk of long COVID-19; however, clinical data on the persistence of gastrointestinal symptoms after COVID-19 in this group are limited, complicating post-infection management and follow-up planning.
Vol.V. Podolskyi, Vas.V. Podolskyi, N.V. Medvedovska, S.V. Osaulenko   +3 more
doaj   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Exploring the effects of reflexology on gastrointestinal symptoms in Type-2 diabetic patients: A quasi-experimental study

Gastroenterology & Endoscopy
Introduction: Type 2 diabetes is a growing global health concern, often leading to gastrointestinal complications that impact quality of life. Reflexology, a non-invasive therapy, may help alleviate these symptoms, but its effects remain unexplored in ...
Mohammad Rostamkhani, Fatemeh Sadat Hoseini, Azam Malek Hoseini, Masoud Etedali, Zahra Mahdavi, Reza Beiranvand, Hooman Mohammad Talebi   +6 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Gastrointestinal symptoms in adults with Fabry disease and their associations with physical and mental health

BMC Gastroenterology
Background Fabry disease is a rare X-linked lysosomal storage disorder that affects multiple organ systems, including the gastrointestinal tract. The aims were to characterize the prevalence, characteristics, and severity of gastrointestinal symptoms in ...
Mina Susanne Weedon-Fekjær, Hege Kampen Pihlstrøm, Harald Weedon-Fekjær, Birgitte Berentsen, Jan Gunnar Hatlebakk, Birgitte Bjerkely, Olga Karin Solberg, Ketil Riddervold Heimdal, Kristin Ørstavik, Trond G. Jenssen, Solrun Sigurdardottir   +10 more
doaj   +1 more source

Date of onset and case status of individuals with gastrointestinal symptoms.

, 2014
Number of individuals in the cohort with gastrointestinal symptoms by date of symptom onset and case status (N = 187), 12–21 December 2012, Kalundborg, Denmark. Individuals not fulfilling the inclusion criteria were excluded from the cohort.
Jannik Fonager (257212), Marianne Adelhardt (629710), Lieke B. van Alphen (132099), Sofie Gillesberg Lassen (456040), Steen Ethelberg (481281), Anna Charlotte Schultz (629708), Jørgen H. Engberg (629711), Frédérique Dorléans (629707), Camilla Dalgaard (629709), Thea Kølsen Fischer (629712)   +9 more
core   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Interpretability of the PedsQL™ Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in Pediatric Patients With Functional and Organic Gastrointestinal Diseases

, 2015
OBJECTIVE: The present study investigates the clinical interpretability of the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Scales and Worry Scales in pediatric patients with functional gastrointestinal disorders or organic ...
Self, Mariella M., Self, Mariella M, Franciosi, James P, Pohl, John F, Zacur, George M., Shulman, Robert J, Pediatric Quality of Life Inventory™ Gastrointestinal Symptoms Module Testing Study Consortium, Franciosi, James P., Varni, James W, Bendo, Cristiane B., Saps, Miguel, Pohl, John F., Bendo, Cristiane B, Saeed, Shehzad, Shulman, Robert J., Varni, James W., Zacur, George M, Saeed, Shehzad Ahmed, Nurko, Samuel, Dark, Chelsea Vaughan, Vaughan Dark, Chelsea   +20 more
core   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source