Results 121 to 130 of about 13,988 (233)
Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu +9 more
wiley +1 more source
Intestinal obstruction (IO) is an important but underexplored complication following simultaneous pancreas‐kidney transplantation (SPKT) and is associated with considerable morbidity and both clinical and economic burdens. In this single‐center cohort study, perioperative parameters, including demographic characteristics, surgical variables, and ...
Rongxin Chen +7 more
wiley +1 more source
Background and Aims: Gastroparesis, characterized by delayed gastric emptying, leads to debilitating gastrointestinal symptoms and often experience comorbid psychiatric disorders, possibly linked to brain-gut network dysfunction.
Karan Sachdeva +19 more
doaj +1 more source
Abstract Introduction Type 1 diabetes mellitus (T1DM) is associated with heightened risk of adverse pregnancy outcomes. Genetic, immune, cardiometabolic, and psychosocial differences exist between childhood‐ and adult‐onset T1DM, yet how these differences may influence pregnancy outcomes remains poorly understood.
Lucas Miranda‐Martinez +3 more
wiley +1 more source
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
Prevalence of hidden gastroparesis in the community: the gastroparesis "iceberg"
Background/Aims: The prevalence of diagnosed gastroparesis is 24.2/100,000 inhabitants, but a large group of people with gastroparesis-like symptoms have never had a gastric emptying (GE) test. Some of them may have undiagnosed gastroparesis. Our aim was
Nicholas Talley (21134759) +5 more
core
Abstract Background Postural orthostatic tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance that primarily affects female patients. There are scarce data evaluating the long‐term outcomes in POTS. Objectives This study sought to evaluate the long‐term impacts of POTS over multiple decades in adult patients.
Kate M. Bourne +11 more
wiley +1 more source
Review article: The diagnosis and management of gastroparesis
BACKGROUND: Gastroparesis is a disorder characterized by a delay in gastric emptying of a meal in the absence of a mechanical gastric outlet obstruction. AIM: To provide an evidence based overview on diagnosis and management of gastroparesis.
Haans, J.J., Masclee, A.A.
core +1 more source
Background Long-standing diabetes mellitus (DM) can lead to macrovascular and microvascular complications, including autonomic neuropathy, which disrupts gut motility.
Mohamed-Naguib Wifi +4 more
doaj +1 more source

