Results 1 to 10 of about 6,554 (119)

Current Nationwide Landscape of Cardiac Surgery for Children With Trisomy 18 in Japan

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Despite the increasing number of retrospective cohorts describing successful cardiac surgery for children with trisomy 18, no consensus has been reached among healthcare providers regarding cardiac surgery in Japan. This study provided a benchmark to facilitate consensus building by assessing a nationwide surgical database in Japan. A total of
Shintaro Nemoto, Hisateru Tachimori, Tomoki Kosho, Kanta Kishi, Noboru Motomura, Yasutaka Hirata   +5 more
wiley   +1 more source

Introducing Novel Surgical Clinical Correlations Into an Undergraduate Medical Anatomy Course

Clinical Anatomy, EarlyView.
ABSTRACT Anatomy education is a hallmark of many preclinical medical school curricula, but students are often unable to identify the clinical relevance of anatomy and its applications. Vertical curricula that integrate clinical concepts into the preclinical basic science years and vice versa have been shown to benefit student learning and increase ...
Liam McLoughlin, Theofano Zoumpou, George P. Holan, Bao‐Ngoc Nasri, Daniel B. Jones, Jeremy J. Grachan   +5 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Combining Detailed Fetal Anatomy Scanning in the NT Window Versus Early Second Trimester Scanning at 14–16 Weeks

Journal of Ultrasound in Medicine, EarlyView.
Objectives First‐trimester ultrasound has evolved to incorporate a detailed fetal anatomy scan (FAS) with nuchal translucency (NT) screening. Many institutions use a 2‐visit protocol: NT followed by detailed FAS at 14–16 weeks. We aimed to evaluate whether integrating detailed FAS into the NT window (12 + 5 to 13 + 6 weeks) is non‐inferior in ...
Tomer Shwartz, Sarah M. Cohen, Michal Lipschuetz, Hila Hochler, Yaron Zalel, Dan V. Valsky, Simcha Yagel   +6 more
wiley   +1 more source

Treatment outcomes in pediatric intestinal failure patients with ambulatory Candida central line‐associated bloodstream infections with and without central venous line removal: A retrospective case series

Nutrition in Clinical Practice, EarlyView.
Abstract Background Lack of central venous line (CVL) sites is a common indication for intestinal transplantation in intestinal failure (IF) patients. For treatment of central line‐associated bloodstream infections (CLABSIs), many pediatric gastroenterologists preserve CVL access, but line removal is typically recommended for Candida sp CLABSI due to ...
Hamza Hassan Khan, Candi S. Jump, Jessica Bauer, Qian Wu, Stephen Thacker, Allison Ross Eckard   +5 more
wiley   +1 more source

Clinical guideline for postoperative nutrition support in neonates with enterostomy (2024)

Pediatric Investigation, EarlyView.
ABSTRACT This is an evidence‐based guideline for postoperative nutritional management of neonates with enterostomy. There were 10 clinical questions in enteral nutrition management, parenteral nutrition management, and post‐discharge follow‐up (including the closure of fistula).
Beijing Children's Hospital, Capital Medical University, National Center for Children's Health | Editorial Board of Chinese Journal of Neonatology | Life Support Group in Neonatologist Subdivision of Chinese Medical Doctor Association   +2 more
wiley   +1 more source

Acute symptoms of depression and traumatic stress in men and women who terminate pregnancy after the detection of fetal anomaly: A prospective observational study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
Abstract Objective To assess acute and long‐term stress in men and women after the detection of fetal anomalies leading to pregnancy termination. Design Prospective observational study. Setting Tertiary referral centre for fetal medicine. Population From the initial sample of 180 pregnant women with a fetal anomaly detected by ultrasound examination, a
Mona Bekkhus, Aurora Oftedal, Guttorm Haugen, Berit Mortensen, Anne Kaasen   +4 more
wiley   +1 more source

Development and Content of Core Outcome Sets in Neonatology—A Scoping Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim To identify subgroups of neonates for whom core outcome sets (COS) have been developed, the outcomes that were included and the methods used in their formulation. Methods We performed a scoping review and searched databases in April 2025 for published COS.
Ilari Kuitunen, Panu Kiviranta, Marjut Haapanen, Peter G. Davis   +3 more
wiley   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón, Nuria Carreras, Tobias Muehlbacher, Dídac Casas‐Alba, Roberta Arena, Paola Roca‐Llabrés, Juan Navarro‐Morón, Linda S. de Vries, Paul Govaert, the EurUS.Brain group, Thais Agut, Roberta Arena, Ana Alarcón, Juan Arnáez, Marco Bartocci, Isabel Benavente‐Fernández, María Carmen Bravo, Fernando Cabañas, Nuria Carreras, Olivier Claris, Jeroen Dudink, Monica Fumagalli, Alfredo García‐Alix, Paul Govaert, Sandra Horsch, Simón Lubián, Tobias Muehlbacher, Alessandro Parodi, Adelina Pellicer, Luca Ramenghi, Charles C. Roehr, Simone Schwarz, Sylke Steggerda, Eva Valverde   +33 more
wiley   +1 more source

A Neonatal Nurse‐Controlled Model of Analgesia to Manage Post‐Operative Pain in the Surgical Neonate: A Pilot Randomised Controlled Trial

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To test the feasibility and acceptability of a newly developed model of neonatal nurse‐controlled analgesia to manage pain in the post‐operative infant. Design The study utilised a single‐centre two‐arm parallel, unblinded randomised controlled external pilot trial design.
Renee Muirhead, Kathryn Kynoch, Glenda Hawley, Emma Ballard, Pita Birch, P. A. Lewis   +5 more
wiley   +1 more source