Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. [PDF]
PLoS ONE, 2014 Myc proteins control cell proliferation, cell cycle progression, and apoptosis, and play important roles in cancer as well in establishment of pluripotency. Here we investigated the control of myc gene expression by the Pou5f1/Oct4 pluripotency factor in
Kay Kotkamp +6 more
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CRISPR/Cas9 establishment-mediated targeted mutagenesis in Macrobrachium nipponense
Frontiers in Physiology, 2023 Introduction: CRISPR/Cas9 is a gene-editing technology which could specifically cleave dsDNA and induce target gene mutation. CRISPR/Cas9 has been widely used in gene functional studies in many fields, such as medicine, biology, and agriculture due to ...
Hui Qiao +10 more
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Early development of the central and peripheral nervous systems is coordinated by Wnt and BMP signals. [PDF]
PLoS ONE, 2008 The formation of functional neural circuits that process sensory information requires coordinated development of the central and peripheral nervous systems derived from neural plate and neural plate border cells, respectively.
Cédric Patthey +2 more
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Zebrafish as a Model for Fetal Alcohol Spectrum Disorders
Frontiers in Pharmacology, 2021 In this review, we will discuss zebrafish as a model for studying mechanisms of human fetal alcohol spectrum disorders (FASDs). We will overview the studies on FASDs so far and will discuss with specific focus on the mechanisms by which alcohol alters ...
Amena Alsakran +2 more
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Metabolites, 2022 Many previous studies have reported the various proteins specifically secreted as inducers in the dorsal or ventral regions in vertebrate gastrula. However, little is known about the effect on cell fate of small molecules below 1000 Da.
Yukako Suzuki +7 more
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Phosphorylation-dependent ubiquitination of paraxial protocadherin (PAPC) controls gastrulation cell movements. [PDF]
PLoS ONE, 2015 Paraxial protocadherin (PAPC) has been shown to be involved in gastrulation cell movements during early embryogenesis. It is first expressed in the dorsal marginal zone at the early gastrula stage and subsequently restricted to the paraxial mesoderm in ...
Masatake Kai +2 more
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Efecto de la salinidad en la embriogénesis del erizo de mar Arbacia stellata (Blainville, 1825)
La Técnica: Revista de las Agrociencias, 2021 El erizo de mar Arbacia stellata puede habitar en ecosistemas estuarinos, pero se desconoce la salinidad crítica en las etapas iniciales de vida para su cultivo.
Edgar Alexander Zapata Vìvenes +3 more
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Sequencing and analysis of the gastrula transcriptome of the brittle star
EvoDevo, 2012 Background The gastrula stage represents the point in development at which the three primary germ layers diverge. At this point the gene regulatory networks that specify the germ layers are established and the genes that define the differentiated states ...
Vaughn Roy +4 more
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Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer
eLife, 2020 Deciphering the mechanisms of axis formation in amphioxus is a key step to understanding the evolution of chordate body plan. The current view is that Nodal signaling is the only factor promoting the dorsal axis specification in the amphioxus, whereas ...
Iryna Kozmikova, Zbynek Kozmik
doaj +1 more source
Differential responses to Wnt and PCP disruption predict expression and developmental function of conserved and novel genes in a cnidarian. [PDF]
PLoS Genetics, 2014 We have used Digital Gene Expression analysis to identify, without bilaterian bias, regulators of cnidarian embryonic patterning. Transcriptome comparison between un-manipulated Clytia early gastrula embryos and ones in which the key polarity regulator ...
Pascal Lapébie +7 more
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