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Long Non-Coding RNA GATA3-AS1 Promotes 5-Fluorouracil Resistance of Ovarian Cancer via Mediating miR-6771-3p/SOX4 Target Axis

Journal of Biomaterials and Tissue Engineering, 2021
Ovarian cancer (OC) ranks as the 5th highest cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) exert significant effects on chemotherapy resistance. The effects of lncRNA GATA3-AS1 on the 5-Fluorouracil (5-FU) resistance in ovarian carcinoma were explored in the current study.
Yafei Hao   +3 more
exaly   +2 more sources

Increased Level of GATA3-AS1 Long Non-Coding RNA Is Correlated With the Upregulation of GATA3 and IL-4 Genes in Multiple Sclerosis Patients

Molecular Biology Reports
Long non-coding RNAs (lncRNAs) play various roles in gene regulation. GATA3 antisense RNA 1 (GATA3-AS1) is an lncRNA gene neighboring GATA binding protein 3 (GATA3). The current study aims to quantitatively compare the levels of the expression of GATA3-AS1, GATA3, and Interleukin-4 (IL-4) in peripheral blood mononuclear cells (PBMC) samples of MS ...
Mohammad Javad Mokhtari   +1 more
exaly   +3 more sources

Helicobacter pylori Promotes Gastric Cancer Progression Through the GATA3-AS1/miR-30c-5p/CTHRC1 Axis.

International Immunopharmacology
Gastric cancer (GC) remains a major global health burden, often diagnosed at advanced stages with poor prognosis. Helicobacter pylori (H. pylori) infection promotes GC development through inflammation and altered signaling. Collagen triple helix repeat containing 1 (CTHRC1), a secreted ECM protein, is upregulated in several cancers and may be involved ...
Yongxiang Li, Mengdi Ma, Kexun Yu
exaly   +3 more sources

LncRNA GATA3-AS1 affects the proliferation and apoptosis of cardiomyocytes through modulating miR-149-3p/NR2F2 axis

Molecular and Cellular Biochemistry
Congenital heart disease (CHD) represents the most prevalent and life-threatening birth defect. The identification of underlying factors contributing to abnormal cardiac development can offer valuable insights for the comprehensive medical management of affected pediatric patients.
Huaming Wang   +5 more
openaire   +2 more sources

[Effect of LncRNA GATA3-AS1 Targeting MiR-515-5p on Cell Proliferation and Apoptosis in Childhood Acute Lymphoblastic Leukemia Cells].

Zhongguo shi yan xue ye xue za zhi, 2023
To investigate the effects of long non-coding RNA (lncRNA) GATA3 antisense RNA 1 (GATA3-AS1) targeting miR-515-5p on the proliferation and apoptosis of childhood acute lymphoblastic leukemia (ALL) cells.RT-qPCR was used to determine the expression of GATA3-AS1 and miR-515-5p in the plasma of controls and ALL children.
Yan, Qin   +4 more
openaire   +1 more source

Correction to: LncRNA GATA3‑AS1 promoted invasion and migration in human endometrial carcinoma by regulating the miR‑361/ARRB2 axis

Journal of Molecular Medicine, 2022
Yu‑xi Liu   +6 more
openaire   +1 more source

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