Results 221 to 230 of about 42,197 (311)

Rethinking Contrast CT in the Emergency Department: Why Pretest Probability, Not Creatinine, Should Guide Our Decisions. [PDF]

Cureus
Sakamoto S.
europepmc   +1 more source

Pemt Inhibition‐Mediated Vdac1 Oligomerization Regulates Mitochondrial Dysfunction, Apoptosis, and Inflammation in High‐Fat Diet‐Derived Liver Injury

Advanced Science, EarlyView.
ABSTRACT High‐fat diet (HFD)‐induced hepatic injury represents a pathology observed across vertebrates, yet the underlying mechanisms remain incompletely understood. Herein, the present study identifies phosphatidylethanolamine methyltransferase (Pemt), a key enzyme in phosphatidylcholine synthesis, as a critical regulator of mitochondrial homeostasis ...
Xianyong Bu, Xiufei Cao, Xin Yao, Baolin Li, Wencong Lai, Zengqi Zhao, Tingting Hao, Zhiwei Chen, Jianlong Du, Yueru Li, Kangsen Mai, Qinghui Ai   +11 more
wiley   +1 more source

Psychometric Properties of the Drug Stigma Scale Among Community Pharmacists Concerning Individuals Who Use Over-The-Counter Drugs. [PDF]

Neuropsychopharmacol Rep
Katayama M, Shimane T, Shirakawa N, Sugiura K, Inada K, Konishi J, Sakurai Y, Kobara K, Fujishiro S, Matsumoto T.   +9 more
europepmc   +1 more source

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Multistate study on suicide risk reduction and improving mental well-being among school and college students in India - an implementation research study protocol. [PDF]

Front Public Health
Mehrotra S, Duggal C, Rustagi N, Ransing RS, Indu PS, Chakraborty S, Mene T, Sharma P, Prasad D, Prinja S, Verma P, Dhamija RK, Kataria K, Munivenkatappa M, Suthar N, Anilkumar TV, Dahiya N, Grover A.   +17 more
europepmc   +1 more source

Polymer‐Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring

Advanced Science, EarlyView.
A monolithic integrated photonic chip simultaneously measures blood glucose, pressure, temperature, ECG, and sweat glucose. Combining multiple Bragg grating sensors, Mach–Zehnder modulators, and an on–‐chip demodulation unit, this compact chip (1 cm × 0.5 cm) offers robust multiparameter detection.
Xiaolin Li, Hongqiang Li, Ming Han, Xin Liu, Mingjun Ding, Ziying Niu, Dongyang Liu, Liyuan Yang, Lizhen Zhang, Francisco Hernández‐Ramírez, Lu Cao, Enbang Li   +11 more
wiley   +1 more source

Advances in Targeting BCR-ABL^T315I Mutation with Imatinib Derivatives and Hybrid Anti-Leukemic Molecules. [PDF]

Molecules
Tuzikiewicz A, Wawrzyniak W, Kutner A, Żołek T.   +3 more
europepmc   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

The effect of oncology-specific suicide prevention program on oncology nurses' levels of suicide literacy, suicide stigma, and efficacy perception for suicide risk management: a randomized controlled study. [PDF]

Support Care Cancer
Öztürk S, Hiçdurmaz D.
europepmc   +1 more source