A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies +14 more
wiley +1 more source
Editorial: Community-centric strategies for HIV and STI prevention in key populations. [PDF]
Mngadi K, Broder GB.
europepmc +1 more source
A Perspective on Interactive Theorem Provers in Physics
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley +1 more source
Becoming one with the community: a grounded theory-derived context-specific framework exploring AIDS service organization strategies for implementing pre-exposure prophylaxis outreach among African American populations. [PDF]
Ayangeakaa SD +5 more
europepmc +1 more source
Competence and Character: The Heart of CLE for the Profession\u27s Gatekeepers [PDF]
Murrell, Patricia H.
core +1 more source
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source
Exploring the Interplay Between Molecular Signaling and Ecosystem Resilience in Plants Under Salt and Water Stress. [PDF]
Jardim AMDRF, Silva TID.
europepmc +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang +11 more
wiley +1 more source

