Results 251 to 260 of about 180,101 (334)

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Bridging the gap: the need for community-engaged research on blood cancer self-management experiences among South Asians. [PDF]

Support Care Cancer
Dhillon S, Sirois AC, Sanghera D, Kaur A, Sasheendren A, Mian H, Newton L, Ahmed S, Cosco TD, Lad D, Bradley C, Puts M, Haase KR.   +12 more
europepmc   +1 more source

Modification Strategies of Carbon‐Based Electrodes From Structural Regulation to Multifunctional Integration

Advanced Science, EarlyView.
Tracing the evolution from structural regulation to multifunctional integration, this paper systematically analyzes modification strategies for carbon‐based electrodes. It evaluates how element doping, surface functionalization, and composite material design affect the electrode performance, and offers perspectives on future applications and challenges
Yunlei Wang, Shitao Dou, Yifan Wu, Mingguang Wang, Taibin Wu   +4 more
wiley   +1 more source

Challenging times in medical education in the era of artificial intelligence can provide opportunities. [PDF]

Clin Med (Lond)
Ala A, Saravanan P.
europepmc   +1 more source

Experimental Joint Estimation of Phase and Phase Diffusion Via Deterministic Bell Measurements

Advanced Science, EarlyView.
This work employs Bell measurement, a form of entangling measurement, to estimate both the phase and its fluctuations in an optical interferometer. By incorporating a novel quantum effect at the measurement stage, the proposed method achieves the ultimate precision limit and demonstrates the significant potential of entangling measurements in multi ...
Ben Wang, Minghao Mi, Huangqiuchen Wang, Qian Xie, Lijian Zhang   +4 more
wiley   +1 more source

From synaptic gatekeepers to affective-cognitive modulators: The astrocyte D1 receptor-d-serine axis in the prefrontal cortex. [PDF]

Acta Pharm Sin B
Fang LP, Kirchhoff F.
europepmc   +1 more source

Microwave Ultrafast Heating on Iron‐based Nanogap Catalysts for CO2 Reduction Coupling with Coke Removal

Advanced Science, EarlyView.
This study employs a nanogap‐induced microwave discharge strategy to pretreat coke deposits on iron‐based catalysts with engineered nanogaps, causing ultrarapid heating to 1990 K within seconds, selectively eliminating >70% surface carbon deposits and converting waste plastics and greenhouse gases into syngas.
Xi Shen, Zhenyu Zhao, Jinsong Zhang, Hong Li, Xin Gao   +4 more
wiley   +1 more source

Addressing the broader implications of AI-AI bias in decision-making systems. [PDF]

Proc Natl Acad Sci U S A
Yu Z.
europepmc   +1 more source

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

Guides, not gatekeepers

Frontiers of Biogeography, 2014
Michael N Dawson, Richard Field, Joaquin Hortal   +2 more
doaj