Results 31 to 40 of about 158,019 (307)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Gatekeepers in a digital wasteland [PDF]

open access: yes, 2013
It is already a cliché to announce the demise of the book in the wake of the digital revolution. While it might be unwise to stake our futures on the printed-and-bound codex, it seems doubtful that a shift in the way words are delivered will result in ...
Eve, Martin Paul
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Deconstructing the discourse of citizen journalism: Who says what and why it matters

open access: yesPacific Journalism Review, 2019
Since it emerged early this century, ‘citizen journalist’ and its related terms have been increasingly contested among groups including professional journalists, academics, and citizens themselves.
Elspeth Tilley, John Cokley
doaj   +1 more source

Inside Lawyers: Friends or Gatekeepers? [PDF]

open access: yes, 2016
Part I of this Article sets the stage by contrasting two alternative proposals to reform the inside lawyer\u27s role—my reform and Hamermesh\u27s counterreform. Part II discusses the primary empirical disagreements between the two approaches.
Kim, Sung Hui
core   +1 more source

The Qualified Legal Compliance Committee: Using the Attorney Conduct Rules to Restructure the Board of Directors [PDF]

open access: yes, 2003
The Securities and Exchange Commission introduced a new corporate governance structure, the qualified legal compliance committee, as part of the professional standards of conduct for attorneys mandated by the Sarbanes-Oxley Act of 2002.
B. Jonsson   +24 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Gatekeepers changing consumers' behaviour in energy consumption [PDF]

open access: yes, 2009
Changing people's behaviour and reducing energy consumption has proved to be more difficult than attitudes or technical possibilities would imply. In this paper we discuss how to intervene the individual decisions that significantly determine energy ...
Kaskinen, Tuuli   +3 more
core  

The IRB as Gatekeeper: Effects on Research with Children and Youth

open access: yes, 2017
Gatekeepers play an important role in research conducted with children and youth. Although qualitative researchers frequently discuss institutional and individual gatekeepers, such as schools and parents, little attention has been paid to the role that ...
Harger, Brent D., Quintela, Melissa
core   +1 more source

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