Results 31 to 40 of about 1,016,504 (289)

Geometric quantum gates robust against stochastic control errors [PDF]

open access: yes, 2004
We analyze a scheme for quantum computation where quantum gates can be continuously changed from standard dynamic gates to purely geometric ones.
L. M. K. Vandersypen   +2 more
core   +1 more source

Gating currents indicate complex gating of voltage-gated proton channels [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
The voltage-gated proton channel (HV1) is a unique molecule that resides at the interface between ion channels and bioenergetic molecules that use proton gradients to store or transduce energy. HV1 plays key roles in the health and disease of diverse tissues and species (1). Important information regarding the physical components of ion-channel gating (
openaire   +2 more sources

New respiratory syncytial virus immunization products in low- and middle-income countries: potential for cost-effective impact on a high burden of disease in young infants

open access: yesBMC Medicine, 2023
As new, efficacious respiratory syncytial virus (RSV) immunization products reach the market, affordable pricing as well as improved estimation of disease burden and the full potential and cost effectiveness of RSV prevention in the hardest hit ...
Padmini Srikantiah, Keith P. Klugman
doaj   +1 more source

Scalability of quantum computation with addressable optical lattices [PDF]

open access: yes, 2008
We make a detailed analysis of error mechanisms, gate fidelity, and scalability of proposals for quantum computation with neutral atoms in addressable (large lattice constant) optical lattices.
B. W. Reichardt   +13 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Analysis of the Impact of Hydraulic Gates on a Stabilized Tidal Inlet Structure: Mathematical Model and Data Measurements

open access: yesHydrology
Tidal inlet structures are engineering projects with associated benefits related to flood control, water quality enhancement, and coastal protection. This study analyzes the performance of hydraulic gates on a stabilized inlet in estuarine systems by ...
Alfonso Arrieta-Pastrana   +2 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Developing a Common Understanding of Networks of Care through a Scoping Study

open access: yesHealth Systems & Reform, 2020
The phrase “Networks of Care” seems familiar but remains poorly defined. A health system that exemplifies effective Networks of Care (NOC) purposefully and effectively interconnects service delivery touch points within a catchment area to fill critical ...
Andy E. Carmone   +6 more
doaj   +1 more source

Self-Testing of Universal and Fault-Tolerant Sets of Quantum Gates

open access: yes, 2000
We consider the design of self-testers for quantum gates. A self-tester for the gates F_1,...,F_m is a classical procedure that, given any gates G_1,...,G_m, decides with high probability if each G_i is close to F_i.
Magniez, Frederic   +3 more
core   +5 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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