Results 131 to 140 of about 1,188,610 (358)

Multi-Hop LoRaWAN Protocol with Efficient Placement of the Relay Nodes

Applied Sciences
Multi-hop networks’ performance strongly depends on relay node placement, which affects delay, throughput, and coverage. This work introduces a dual-layer protocol combining Slotted ALOHA for node-to-relay communication and TDMA for relay-to-gateway ...
Konstantina Spathi, Anastasios Valkanis, Georgia Beletsioti, Konstantinos Kantelis, Georgios Papadimitriou, Petros Nicopolitidis   +5 more
doaj   +1 more source

I-TASSER gateway: A protein structure and function prediction server powered by XSEDE

Future generations computer systems, 2019
There is an increasing gap between the number of known protein sequences and the number of proteins with experimentally characterized structure and function.
Wei Zheng, Chengxin Zhang, Eric W. Bell, Yang Zhang   +3 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Examining the socio-economic determinants of adoption of the 'Government Gateway' initiative in the UK

, 2006
This paper empirically examines the impact of socio-economic determinants upon the adoption of a recent UK e-government initiative, the 'Government Gateway'. The data on five socio-economic characteristics was collected employing a postal survey.
Dwivedi, YK, Yogesh Dwivedi, Khoumbati, K, Gharavi, H, Papazafeiropoulou, A   +4 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Gateways

Information Services & Use, 1988
Gateways have come to stand for many different things – interconnectivity, reseller, marketing, administrative – functions that are performed on the behalf of another vendor. Many discussions suggest that a gateway is, in fact, a surrogate information service.
openaire   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Gateway National Recreation Area program guide.

Description based on: Vol. 1, no. 3 (fall/winter 1990); title from caption.Mode of access: Internet.Split into: Gateway National Recreation Area (Agency : U.S.). Jamaica Bay Unit.
Gateway National Recreation Area (Agency : U.S.)
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Effect of Photobiomodulation Therapy Dosage on Orthodontic Movement, Temporomandibular Dysfunction and Third Molar Surgery Outcomes: A Five-Year Systematic Review

Applied Sciences
(1) Background: This five-year systematic review seeks to assess the impact of oral and peri-oral photobiomodulation therapies (PBMTs) on the adjunctive management of deeper tissue biofunction, pathologies related to pain and inflammatory disorders and ...
Steven Parker, Mark Cronshaw, Eugenia Anagnostaki, Valina Mylona, Edward Lynch, Martin Grootveld   +5 more
doaj   +1 more source