Results 161 to 170 of about 1,188,610 (358)
The Rhetoric of the iPhone: A Cultural Gateway Of Our Transforming Digital Paradigm
, 2017 The metaphors “tipping point” and “paradigm shift” are used to describe the moments surrounding social and scientific changes; however, I argue that in examining changes in culture and communication, the role of technology suggests the need for a new ...
Rose, Jessica
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Keamanan Kendaraan Sepeda Motor Berbasis WIFI dengan kontrol SMS Gateway
, 2017 Keamanan sepeda motor menjadi salah satu kebutuhan masyarakat saat ini. Hal ini didasari dengan meningkatnya tingkat pencurian dan perampasan sepeda motor tiap tahunnya.oleh karena itu, Penelitian ini bertujuan untuk :Membuat dan Mengimplementasikan ...
Laode Satriyono Safiun +3 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Gateway Cloning Vector Set for High-Throughput Functional Analysis of Genes in Planta[w]
Plant Physiology, 2003 M. Curtis, U. Grossniklaus
semanticscholar +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2010 Includes bibliographical references.With the end of apartheid, many South Africans were anticipating improved living conditions and a better quality of life.
Kallay, Natasha Kate
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
, 2012 Social Capital Gateway (SCG) is a web site publishing materials for the study of social capital and related topics in a multidisciplinary ...
SABATINI, FABIO
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source