Results 41 to 50 of about 120,568 (187)

Human FASTK preferentially binds single‐stranded and G‐rich RNA

The FEBS Journal, EarlyView.
Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak, Dawid A. Dzadz, Mikołaj I. Kuska, Madhuri Kanavalli, Maria M. Klimecka, Matthew Merski, Katarzyna J. Bandyra, Maria W. Górna   +7 more
wiley   +1 more source

HaIRST: Harvesting Institutional Resources in Scotland Testbed. Final Project Report [PDF]

, 2005
The HaIRST project conducted research into the design, implementation and deployment of a pilot service for UK-wide access of autonomously created institutional resources in Scotland, the aim being to investigate and advise on some of the technical ...
Dunsire, Gordon
core  

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus

The FEBS Journal, EarlyView.
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen, Jan Eric Maika, Raphael Josef Eberle, Nina Jahnke, Marcel Wiermer, Laura Hartmann, Rüdiger Simon, Georg Groth   +7 more
wiley   +1 more source

Psoriasis‐like inflammation induces structural and functional changes in mitochondria

The FEBS Journal, EarlyView.
Psoriasis‐like inflammation, induced by IL‐17, IL‐22, and TNF‐α in keratinocytes and fibroblasts, alters mitochondrial functions, suppressing respiration and increasing mitochondrial ROS production. It also triggers mitochondrial fragmentation, swelling, and cristae disassembly, alongside enhanced secretion of proinflammatory mediators driven by ...
Gabrielė Kulkovienė, Martyna Uldukytė, Sofiya Haluts, Milda Kairytė, Jonas Šoliūnas, Viktorija Šalčiūtė, Rūta Inčiūraitė, Jurgita Skiecevičienė, Monika Iešmantaitė, Ramunė Morkūnienė, Aistė Jekabsone   +10 more
wiley   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

Sistem Manajemen Hubungan Pelanggan Berbasis Web Dengan Fitur SMS Gatway Pada Simply Fresh Laundry Outlet 63 Palembang [PDF]

Pembuatan proposal ini bertujuan untuk membantu pihak perusahaan dalam penyampaian informasi dan promosi mengenai sistem informasi manajemen hubungan pelanggan berbasis web dengan menggunakan fitur SMS gateway untuk mempermudah dalam hal promosi ...
Harahap, Choirul Syarfi, Putri, Okstria Mahendra   +1 more
core  

‘It's Like a Horror Movie That You Walk Through’: Experiencing Horror Through Immersive Recreation

The Journal of American Culture, EarlyView.
ABSTRACT Horror stories have provided enjoyable forms of leisure for centuries. Over the past five decades, however, these experiences have evolved into increasingly immersive forms of popular culture. What once involved constructing the narrative world internally through reading has expanded into sensory engagement through visual and auditory media ...
Susan Weidmann
wiley   +1 more source

Top Level Mesh [PDF]

, 2019
This paper will cover our report on the Top Level Mesh. We have built a web-based system for mesh network management. This system allows network utilities to be used from a web-based interface to monitor and manage the transfer of data.
Islam, Tristen, Jasaitis, Matt
core   +1 more source

Rancang Bangun Sistem Informasi Pemantauan Perkembangan Anak di Yayasan Bina Autis Mandiri Palembang Berbasis Web dan SMS Gateway [PDF]

Tujuan dari penulisan skripsi ini adalah membantu Yayasan Bina Autis Mandiri Palembang dalam penyampaian informasi kepada orang tua / wali siswa dan pihak eksternal melalui rancangan aplikasi sistem informasi berbasis Web dan SMS Gateway. Metode
F., Hilma Yuliana S., Rahayu, Eva
core