Results 101 to 110 of about 37,179 (261)
The Journal of Pathology, EarlyView.Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim +9 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield of integrated molecular autopsy (IMA) by combining deep post‐mortem phenotyping with exome (ES) and targeted genome sequencing (GS) for prenatally detected anomalies. Method This retrospective study evaluated 28 perinatal cases (22 fetuses, six neonates) with severe anomalies, normal first‐tier ...
Sihem Darouich +6 more
wiley +1 more source
Design and evaluation of a genomics variant analysis pipeline using GATK Spark tools [PDF]
Scalable and efficient processing of genome sequence data, i.e. for variant discovery, is key to the mainstream adoption of High Throughput technology for disease prevention and for clinical use.
Tucci N, Cala J, Missier P, Steyn J
core +4 more sources
PLOS ONE, 2015 The Data Accession section of this paper is incorrect. The section should say: The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are available from Figshare: http://dx.doi.org/10.6084/m9.figshare.1509777.
Pengyuan Zhu +11 more
openaire +3 more sources
PLANTS, PEOPLE, PLANET, EarlyView.Evergreen broadleaved forests (EBLFs) represent an iconic vegetation type in subtropical montane East Asia, but they are experiencing intensifying anthropogenic pressure and increasing habitat fragmentation. Here, using a dominant and widespread tree species characteristic of East Asian EBLFs, we examine its phylogeographic history and evaluate what it
Sheng‐Yuan Qin +7 more
wiley +1 more source
Using Whole Genome Sequencing to Decipher the Metschnikowia pulcherrima Complex
Yeast, EarlyView.ABSTRACT Metschnikowia pulcherrima, an ascomycetous yeast, has been frequently isolated from various substrates associated with agriculture such as nutrient‐rich plant materials (fruit, fruit juices and fermenting grape must), soil and with various insects including fruit flies.
El Khoury Samer +4 more
wiley +1 more source
Summary of DNM candidates identified in GATK based on Mendelian violations.
Summary of DNM candidates identified in GATK based on Mendelian violations.
Frances Patel (17952113) +10 more
core +1 more source
Integrative Zoology, EarlyView.This study presents the first genomic identification and characterization of ZW sex chromosomes in two soft‐shelled turtle species through genome assembly and resequencing. We reveal the structural organization of ZW chromosomes, identifying both pseudoautosomal regions (PARs) and differentiated regions.
Jianjun Liu +9 more
wiley +1 more source
Genomics, Proteomics & Bioinformatics, 2018 The rapid development of high-throughput sequencing technologies has led to a dramatic decrease in the money and time required for de novo genome sequencing or genome resequencing projects, with new genome sequences constantly released every week.
Wanfei Liu +8 more
doaj +1 more source
Decades of Enclosure Protection Exert Composite Effects on Grassland Grasshopper Communities
Integrative Zoology, EarlyView.Decades of enclosure protection have altered grasshopper community structure, with species‐specific effects on population dynamics. For the low‐mobility grasshopper Chorthippus fallax, abundance did not differ strongly between exclosure‐protected and overgrazed areas, but its egg development duration was longer in exclosures. The two C.
Dan‐dan Feng +7 more
wiley +1 more source