Results 61 to 70 of about 12,915 (236)

Tracking Genetic Parkinson's Disease with Molecular Imaging: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is a worldwide, complex neurodegenerative disorder influenced by both genetic and environmental factors. Around 15–20% of PD cases are linked to genetic mutations, providing insights into the disease's pathogenesis.
Chiara Meneghini, Luca Gallo, Arianna Sala, Enza Maria Valente, Micol Avenali, Silvia Paola Caminiti   +5 more
wiley   +1 more source

N,N′-(Ethane-1,2-diyl)dibenzenecarbothioamide

Acta Crystallographica Section E, 2014
The title compound, C16H16N2S2, adopts a gauche+–gauche+–gauche+ (g+g+g+) conformation in the NH—CH2—CH2—NH bond sequence. In the crystal, molecules are connected by pairs of N—H...S=C hydrogen bonds and C—H...π interactions, forming a tape structure ...
Masayuki Nagasawa, Yuji Sasanuma, Hyuma Masu   +2 more
doaj   +1 more source

Associations of Monocyte Glucocerebrosidase with Cognition and Cholinergic Innervation in GBA1 Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background The GBA1 gene encodes the lysosomal enzyme glucocerebrosidase (GCase). Parkinson's disease (PD) patients carrying a GBA1 variant (GBA‐PD) exhibit faster cognitive decline, linked to cholinergic degeneration. Objectives The aim was to investigate whether GCase activity, measured in monocytes, correlates with cognitive dysfunction or ...
Sofie Slingerland, Sygrid van der Zee, Sven C.D. van Ijzendoorn, Anne C. Slomp, Jeffrey M. Boertien, Sanne K. Meles, Arjan Kol, Marie Geerlings, Teus van Laar   +8 more
wiley   +1 more source

Study on Isolation and Raman Spectroscopy of Glycinin in Soybean Protein

Grain & Oil Science and Technology, 2018
The secondary structures of soybean glycinin was investigated by Raman spectroscopy and its acidic and basic polypeptides were isolated. The results showed that the secondary structures of glycinin were mainly composed of 21.51% α-helix, 41.62% β-sheet ...
YIN Haicheng, HUANG Jin, ZHANG Huiru
doaj   +1 more source

The GBA1 p.E427K (p.E388K) Variant Is a Risk Factor for Synucleinopathies: A Meta‐Analysis

Movement Disorders, EarlyView.
Abstract Background Variants in GBA1 are important genetic risk factors for synucleinopathies, including Parkinson's disease (PD). Although several GBA1 variants are established risk or severity modifiers, the role of the p.E427K variant remains unclear.
Leah V. Chifamba, Sitki Cem Parlar, Emma N. Somerville, Lang Liu, Eric Yu, Farnaz Asayesh, Jamil Ahmad, Meron Teferra, Jennifer A. Ruskey, Cheryl Waters, Oury Monchi, Yves Dauvilliers, Nicolas Dupré, Alla Timofeeva, Anton Emelyanov, Sofya Pchelina, Irina Miliukhina, Lior Greenbaum, Sharon Hassin‐Baer, Orly Goldstein, Mandy Radefeldt, Peter Bauer, Christian Beetz, Allison A. Dilliott, James C. Beck, Konstantin Senkevich, ROPAD Study Group, The Parkinson's Foundation PD GENEration Study, Christine Klein, Roy N. Alcalay, Ziv Gan‐Or   +30 more
wiley   +1 more source

Evaluation of food safety in the handling of home enteral nutrition based on a new contamination risk classification: A cross‐sectional study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Home enteral nutrition (HEN) offers clinical benefits and is increasingly used, although handling‐related health risks remain unclear. This study assessed food safety in HEN using a new contamination risk classification. Methods First, the inter‐rater reliability of the Food Safety for Handling HEN checklist was analyzed in 25 ...
Elaine Cristine de Souza Martins, Caroline Opolski Medeiros, Rayane Luizi da Costa, Luciana Karbiak, Márcia Regina Beux, Diego Averaldo Guiguet Leal, Lize Stangarlin‐Fiori   +6 more
wiley   +1 more source

Une tumeur hépatique rare chez l'enfant: l'hyperplasie nodulaire focale

The Pan African Medical Journal, 2014
Les tumeurs hépatiques de l'enfant sont rares, elles représentent 1 à 4 % des tumeurs solides. L'hépatoblastome est le chef de fil des masses hépatiques. Nous rapportons le cas d'un garçon de 4 ans, déjà suivi pour une hémihypertrophie corporelle gauche,
Mohamed Rami, Youssef Bouabdallah
doaj   +1 more source

La Resolución 1325 del Consejo de Seguridad de las Naciones Unidas. A 15 años de su adopción

Revista Tribuna Internacional, 2016
Con la adopción de la Resolución 1325 por el Consejo de Seguridad de las Naciones Unidas en el año 2000, se dio inicio a una etapa en que una agenda institucional sobre igualdad de las mujeres en el ámbito de la paz y la seguridad internacional ha ...
Ximena Gauché Marchetti
doaj   +1 more source

Neuroimaging Findings and Risk Factors for Brain Injury in Foetuses Treated for Anaemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Characterize neuroimaging findings in foetuses with anaemia and identify associated risk factors. Methods Retrospective cohort study of pregnancies with foetal anaemia (defined as haemoglobin > 2 standard deviations below the gestational age mean) confirmed by foetal blood sampling (FBS) and treated with intrauterine transfusion (IUT)
Laurence Sophie Carmant, Carlos Robles, Seungwoo Lee, Prakesh S. Shah, Greg Ryan, Elka Miller, Shiri Shinar   +6 more
wiley   +1 more source

Fabrication of amorphous lamellar freestanding poly(N‐dodecyl acrylamide) films and their mechanical properties

Polymer International, EarlyView.
A freestanding film of completely uniaxially oriented amorphous lamellae was produced. The film exhibited enhanced tensile strength with increasing orientation of the lamella. Abstract An amorphous lamellar freestanding film composed of poly(N‐dodecyl acrylamide) (pDDA) was prepared by annealing a micrometer‐thick film under humid conditions (humid ...
Yuki Koizumi, Yoshimasa Matsuo, Akito Masuhara, Hinako Ebe, Yuya Ishizaki‐Betchaku, Shusaku Nagano, Jun Matsui   +6 more
wiley   +1 more source