Results 41 to 50 of about 5,176,506 (186)
Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines
Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt +3 more
wiley +1 more source
Pulmonary involvement in adult Gaucher's disease: High resolution CT appearance
, 2022 High resolution CT findings of pulmonary involvement are described in a patient with adult type Gaucher's disease. Although the reticular pattern on the chest radiograph was typical, appearance of pulmonary involvement on high resolution CT has not been ...
Arat, A +3 more
core +1 more source
Failure of treatment of Coxa Vara in Gauchers Disease: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2012 Gaucher’s disease (GD) is an autosomal recessive storage disorder which occurs due to the deficient functioning of the lysosomal hydrolase enzyme [1, 2]. In this case report, coxa vara occurred after the union of a stress fracture in the basicervical
Sachin Khullar +3 more
doaj
A Solid‐Phase Approach to Chiral C2‐Substituted Cyclen and DOTA‐Like Lanthanoid Ligands
Chemistry – A European Journal, EarlyView.Chiral C2‐substituted cyclen derivatives have been designed and synthesized from chiral cyclic peptoids. Their conversion into the corresponding DOTA‐type ligands opens new avenues for the development of high‐relaxivity MRI contrast agents. ABSTRACT Magnetic resonance imaging (MRI) is a powerful diagnostic modality that relies on Gd+3‐based contrast ...
Rosaria Schettini +9 more
wiley +1 more source
Gaucher’s disease: orphan disease in pediatric practice
Лечащий Врач, 2021 Approaches to diagnostics and treatment of Gaucher’s disease in children were considered. A clinical case is given.
T. A. Bokova
doaj
The Canadian Journal of Chemical Engineering, EarlyView.Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía +3 more
wiley +1 more source
Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria
Nature Communications, 2023 β-Glucocerebrosidase (GCase) mutations lead to glucosylceramide build-up in the lysosome, impacting α-synuclein aggregation and autophagy. Recently, Baden and colleagues found GCase in mitochondria, supporting mitochondrial complex I function and energy ...
Andrés D. Klein, Tiago Fleming Outeiro
doaj +1 more source
Journal of Obstetrics and Gynaecology, 2009 Gaucher disease (GD) is a lysosomal storage disorder (LSD) caused by deficiency of lysosomal β-glucocerebrosidase and subsequent accumulation of glucosylceramide (GlcCer) in cells of the reticuloen...
A M, Mamopoulos +3 more
openaire +2 more sources
Pseudotumor formation in tibia in Gaucher's disease
, 1998 A very rare case of type 1 Gaucher's disease with pseudotumor formation in the right tibia is presented. In addition to the characteristic radiographic finding of distal femoral flaring (Erlenmeyer flask deformity), a lobulated osteolytic area with ...
Gurakan, F +4 more
core +1 more source
PATIENTS AT RISK OF THEIR ETHNIC BACKGROUND [PDF]
Romanian Journal of Pediatrics, 2009 This article discuss genetic disorders that appear with increased frequency in certain ethnic groups: – Ashkenazi jews: Tay-Sachs disease, adult Gaucher’s disease – type I, Niemann-Pick disease, mucolipidosis (type IV), pentosuria, Bloom syndrome ...
Valeriu Popescu
doaj +1 more source