Results 71 to 80 of about 4,682 (148)
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.ABSTRACT The purpose was to evaluate retrieval‐augmented generative (RAG) artificial intelligence (AI) methods for assessing the regulatory compliance of drug information and adherence to best practices in clinical trial protocols. Integrated systems containing RAG and large language model (LLM) components were employed to evaluate drug information and
Shreyas Waikar +2 more
wiley +1 more source
Cardiopulmonary assessment of patients diagnosed with Gaucher's disease type I. [PDF]
Mol Genet Genomic Med, 2021 Bjelobrk M +7 more
europepmc +1 more source
What Is a Digital Twin in QSP, and Are We Doing It Right?
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.ABSTRACT The field of Quantitative Systems Pharmacology continues to innovate new methods to derive insights from clinical data. In the past few years, Digital Twins have emerged as a “new” way of deriving patient‐specific model parameterizations to inform possible outcomes for novel scenarios using limited clinical data.
Justin Feigelman
wiley +1 more source
Rare Case of Gaucher's Disease Presenting as a Solitary Swelling of the Proximal Tibia Mimicking a Musculoskeletal Tumor in an Adult: A Case Report. [PDF]
J Orthop Case Rep, 2022 Rahman SH +5 more
europepmc +1 more source
The Journal of Dermatology, Volume 53, Issue 3, Page 380-387, March 2026.ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley +1 more source
Pre- and post-therapeutic evaluation of liver and spleen in type I and type III Gaucher's disease using diffusion tensor imaging. [PDF]
Abdom Radiol (NY), 2022 Alnaghy E, Razek AA, Abdelhalim E.
europepmc +1 more source
Epidemiology of progressive intellectual and neurological deterioration in UK children
Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 418-428, March 2026.This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity +3 more
wiley +1 more source
New correlations between ocular parameters and disease severity in Spanish patients with Gaucher's disease Type I. [PDF]
PLoS One, 2021 Esteban O +6 more
europepmc +1 more source
Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions
Traffic, Volume 27, Issue 1, March 2026.Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang +7 more
wiley +1 more source
Physiological Reports, Volume 14, Issue 5, March 2026.The Stroop test and cold pressor test elicit comparable common carotid artery vasodilation. However, mental stress induced by the Stroop test leads to an earlier peak response, possibly influenced by anticipatory mechanisms. Created in BioRender. Speretta, G. (2026) https://BioRender.com/mwpc1hw.
Francisco J. Fensterseifer +5 more
wiley +1 more source