Results 1 to 10 of about 12,215,968 (180)

Phagocytosis of Erythrocytes from Gaucher Patients Induces Phenotypic Modifications in Macrophages, Driving Them toward Gaucher Cells. [PDF]

Int J Mol Sci, 2022
Gaucher disease (GD) is caused by glucocerebrosidase deficiency leading to the accumulation of sphingolipids in macrophages named “Gaucher’s Cells”. These cells are characterized by deregulated expression of cell surface markers, abnormal secretion of ...
Dupuis L, Chauvet M, Bourdelier E, Dussiot M, Belmatoug N, Le Van Kim C, Chêne A, Franco M.   +7 more
europepmc   +3 more sources

Gaucher Disease and Gaucher Cells [PDF]

Turkish Journal of Hematology, 2015
4. Özsoylu S, Allahverdi H, Laleli Y, Pirnar A. Platelet survival in childhood idiopathic thrombocytopenic purpura in remission. J Pediatr 1976;89:388-390. 5. Özsoylu Ş, Karabent A, Irken G, Tuncer M.
Sevgi Gözdaşoğlu
doaj   +3 more sources

Gaucher Cells or Pseudo-Gaucher Cells: That's the Question [PDF]

Turkish Journal of Hematology, 2014
To the Editor, Bone marrow cells with morphological characteristics similar to Gaucher cells and without cytoplasmic crystalline inclusions are rare.
Deniz Gören Şahin, Hava Üsküdar Teke, Mustafa Karagülle, Neslihan Andıç, Eren Gündüz, Serap Işıksoy, Olga Meltem Akay   +6 more
doaj   +3 more sources

Gaucher-like Cells in Thalassemia Intermedia: Is It a Challenge?

Diseases, 2023
We describe two cases of thalassemia intermedia (TI) patients with the presence of Gaucher-like cells in hematopoietic tissue biopsies, raising diagnostic dilemmas. The first is a 56-year-old female with bone lesions, splenomegaly, hypochromic microcytic
Veroniki Komninaka, Pagona Flevari, Georgios Karkaletsis, Theodoros Androutsakos, Theofili Karkaletsi, Ioannis Ntanasis-Stathopoulos, Evaggelia-Eleni Ntelaki, Evangelos Terpos   +7 more
doaj   +3 more sources

Toxicity of glucosylsphingosine (glucopsychosine) to cultured neuronal cells: a model system for assessing neuronal damage in Gaucher disease type 2 and 3

Neurobiology of Disease, 2003
Patients with Gaucher disease have been classified as type 1 nonneuronopathic, type 2 acute neuronopathic, and type 3 chronic neuronopathic phenotypes. Increased quantities of glucocerebroside and glucosylsphingosine (glucopsychosine) are present in the ...
U.H Schueler, T Kolter, C.R Kaneski, J.K Blusztajn, M Herkenham, K Sandhoff, R.O Brady   +6 more
doaj   +3 more sources

Integrating Gaucher disease (GD) into mainstream hematological curriculum training. [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 10, October 2026.
Bradley C, Symeonidis A, Salek S, Jacob N.   +3 more
europepmc   +2 more sources

Gaucher or pseudo-Gaucher cells. [PDF]

Blood Res
Kaur G, Ahuja A, Vishwananthan GK, Sen A.   +3 more
europepmc   +2 more sources

Diagnostic Challenge of Pediatric Gaucher Disease in a Low‐Resource South Asian Setting: A Case Report [PDF]

Clinical Case Reports
Gaucher disease is a rare autosomal recessive lysosomal storage disorder that is caused by a deficiency of the enzyme “β‐glucocerebrosidase”, leading to the accumulation of glucocerebroside within macrophages. It commonly presents with hepatosplenomegaly,
Muhammad Waqas, Rahila Bano, Muhammad Usman Haider, Kumar Abhishek, Arshad Mehmood, Aqeel Abbas, Abbas Ali, Talha Basheer, Rafiya Muhammad Altaf, Yahya Samadi   +9 more
doaj   +2 more sources

Exploring delayed diagnosis in Gaucher disease: insights from a community survey and potential solutions [PDF]

Orphanet Journal of Rare Diseases
Background Gaucher disease is a rare lysosomal storage disorder caused by insufficient activity of the enzyme β-glucocerebrosidase. This leads to the accumulation of fatty deposits in cells and tissues and damages multiple organ systems.
Diana Paulina Peña Aragón, Tanya Collin-Histed, Magy Abdelwahab, Jesús Villarrubia Espinosa, Raul Chertkoff, Andre Balzekiene, Jessica Pacey   +6 more
doaj   +2 more sources

Integrating paroxysmal nocturnal hemoglobinuria (PNH) into mainstream hematological curriculum training [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 10, October 2026.
Griffin M, Kelly R, Bradley C, Salek S, Soutar R, Symeonidis A.   +5 more
europepmc   +2 more sources