Results 111 to 120 of about 9,175 (221)

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4619-4639, July 2026.
Re‐engineering potato as a biosafe and host‐optimised platform for plant molecular farming by integrating intrinsic biological traits with targeted engineering strategies. ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being ...
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Gaucher Disease

, 2001
Gaucher disease is a rarely seen autosomal recessive disorder associated with enzyme defect. Most commonly seen among Ashkenazian Jewish and its incidence in U.S.A is between 1110.000-20.0000.
Bilgiçli, Nesrin, Aksoy, Faruk, Borazan, Ali, Vatansev, Celalettin   +3 more
core  

Investigation of Combined Alkaline Pretreatment and Mechanoenzymatic Processing for Improved Valorization of Post‐Consumer Textiles

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
This study introduces a targeted mechanochemical pretreatment in a wet rotor mill, which is integrated into a mechanoenzymatic hydrolysis process to valorize mixed cotton textiles. Sodium hydroxide–assisted milling enhances processability and cellulose accessibility.
Miriam Magdalena Schaake, Oliver Pikhard, Moritz Bross, Zhi Cheng Hua, Katrin Suering, Frank Kleine Jaeger, Andreas Liese, Stefan Heinrich   +7 more
wiley   +1 more source

Coexistence of Gaucher Disease and severe congenital neutropenia

, 2019
Gaucher Disease (GD) is the most common lysosomal storage disorder has traditionally been classified into three clinical phenotypes. Type 3 GD is characterized by neurological involvement but neurological symptoms generally appear later in life than in ...
Canda, Ebru, Onay, Huseyin, Karapinar, Deniz, Özkınay, Ferda, Kose, Melis Demir, Ucar, Sema Kalkan, Sozmen, Eser Yildirim, Coker, Mahmut, Kagnici, Mehtap   +8 more
core   +1 more source

The Expression and Secretion Profile of TRAP5 Isoforms in Gaucher Disease

Cells
Background: Gaucher disease (GD) is caused by glucocerebrosidase (GCase) enzyme deficiency, leading to glycosylceramide (Gb-1) and glucosylsphingosine (Lyso-Gb-1) accumulation.
Margarita M. Ivanova, Julia Dao, Neala Loynab, Sohailla Noor, Neil Kasaci, Andrew Friedman, Ozlem Goker-Alpan   +6 more
doaj   +1 more source

Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages

, 2004
Although the existence of anti-inflammatory alternatively activated macrophages (aamphi) has been accepted widely based on in vitro studies, their in. vivo location, phenotype, and function still are debated.
Mehta, A, Boven, Leonie A., Boon, Louis, Aerts, Johannes M., Aerts, JMFG, Boven, LA (Leonie), Mehta, Atul, Boon, L, Boot, RG, Laman, Jon, van Meurs, Marjan, Boot, Rolf G., Laman, Jon D.   +12 more
core   +1 more source

Aproximació terapèutica per a la malaltia de Gaucher basada en xaperones [PDF]

, 2011
[cat] En aquesta tesi s’ha realitzat una aproximació terapèutica per a la malaltia de Gaucher, basada en xaperones farmacològiques. La malaltia de Gaucher és una malaltia d’acúmul lisosòmic d'herència autosòmica recessiva, causada per mutacions en el ...
Sànchez Ollé, Gessamí
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What hematologist needs to know about Gaucher disease

, 2013
Hematological symptoms can be helpful for the diagnosis of inherited metabolic disorders, including Gaucher disease. Gaucher disease is a progressive, multisystem lysosomal storage disorder caused by the deficient activity of the lysosomal enzyme ...
Machaczka, Maciej; Hematology Center Karolinska, Karolinska University Hospital Huddinge, Head: prof. dr med. Per Ljungman, Stockholm, Sweden; Division of Hematology, Department of Medicine at Huddinge, Karolinska Institutet, Head: prof. dr med. Jan Bolinder, Stockholm, Sweden
core   +1 more source

Role of the phagocytosis of sphingolipid overloaded red blood cells in Gaucher disease pathophysiology

, 2020
La Maladie de Gaucher est une maladie génétique rare caractérisée par une déficience enzymatique de la ß-glucocérébrosidase (GCase), conduisant à une accumulation de sphingolipides (SL) dans les macrophages appelés alors Cellules de Gaucher.
Dupuis, Lucie
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Allogenic bone marrow transplantation in severe Gaucher disease.

, 1992
Gaucher disease is the most prevalent lysosomal storage disease. This autosomal recessive disease is caused by the defective activity of the enzyme acid beta-glucosidase and the resultant accumulation of glucosylceramide primarily within cells of the ...
Rankin, L R, Lipton, J M, Najfeld, V, Tsai, P, Ludman, M, Sahdev, I, Grabowski, G A, Slyper, A H   +7 more
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