Results 11 to 20 of about 16,012 (163)

Polygenic scores of Core 1 Alzheimer's disease biomarkers predict early cognitive and pathological change. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Core 1 biomarkers, such as amyloid positron emission tomography, capture the earliest biological changes leading to Alzheimer's disease (AD). While APOE is a major genetic factor, the contribution of other variants to Core 1 biomarkers remains unclear.
Xu Y, Qiao M, Gunasekaran TI, Gu Y, Reyes-Dumeyer D, Piriz A, Sanchez D, Soriano B, Franco Y, Coronado ZD, Recio P, Mejia DR, Medrano M, Lantigua RA, Honig L, Wilson R, Manly JJ, Brickman AM, Engelman CD, Johnson S, Asthana S, Vardarajan B, Mayeux R.   +22 more
europepmc   +2 more sources

Polygenic Risk Scores for Amyloidosis as Predictors of Early changes in Alzheimer's Disease Endophenotypes [PDF]

Alzheimers Dement
Abstract Background Early identification of individuals at risk for Alzheimer's disease (AD) is critical for effective intervention. Amyloid deposition, a hallmark of AD pathology, offers insights into genetic factors driving disease progression. While the APOE genotype is a major contributor, the role of other risk variants in amyloid deposition and ...
Xu Y, Qiao M, Gunasekaran T, Gu Y, Reyes‐Dumeyer D, Piriz A, Sanchez D, Soriano B, Franco Y, Coronado Z, Recio P, Mejia D, Medrano M, Lantigua R, Reyes R, Wilson R, Manly J, Brickman A, Engelman C, Johnson S, Asthana S, Vardarajan B, Mayeux R.   +22 more
europepmc   +2 more sources

Topology optimization considering self‐weight

Proceedings in Applied Mathematics and Mechanics, Volume 23, Issue 4, December 2023., 2023
Abstract In civil engineering self‐weight loading usually represents the preponderant load case and shall therefore be considered in structural optimization. The present study investigates numerical topology optimization of structural stiffness with a bound on disposable amount of material. A customized topology optimization routine based on Sequential
Daniela Masarczyk, Detlef Kuhl
wiley   +1 more source

La evolución de la construcción del Templo de la Sagrada Familia

Informes de la Construccion, 2009
El Templo de la Sagrada Familia (Barcelona, 1882–hoy) es, aun inacabado, una de las obras más importantes de Gaudí y uno de los máximos exponentes de la arquitectura modernista catalana.
R. Espel, J. Gómez, R. Grima, A. Aguado
doaj   +1 more source

90 años de nueva cultura “nanban”

Comillas Journal of International Relations, 2020
Es conocido el aprecio de los japoneses por Dalí, Picasso, Miró, Dalí, Falla, Albéniz o, sobre todo, Gaudí y el flamenco. Más allá, sin embargo, hay influencias y presencias de la cultura española no tan conocidas en algunos de los más relevantes ...
José Antonio de Ory
doaj   +1 more source

Knowing things and going places

European Journal of Philosophy, Volume 31, Issue 1, Page 266-282, March 2023., 2023
Abstract When I say “I know Sarah,” or “I know Berlin,” what sort of knowledge am I claiming? Such knowledge of a particular is, I claim, not reducible to either propositional knowledge‐that or to traditional physical know‐how. Mere, bare knowledge by acquaintance also does not capture the kind of knowledge being claimed here.
Quill R Kukla
wiley   +1 more source

Antonio Gaudí, the forerunner of sustainability and biomimicry in architecture, 100 years in advance [PDF]

, 2018
Objetivo: La sostenibilidad en la arquitectura es uno de los grandes retos del siglo XXI. En la arquitectura biomimética, la naturaleza es el modelo a seguir en la búsqueda de la misma, puesto que nos enseña cuáles son los modelos de funcionamiento más ...
Adell Argilés, José María, Bedoya Frutos, César, Salas Mirat, Carlos   +2 more
core   +4 more sources

Motivation for improving academic achievement in cosmetological education

Health Science Reports, Volume 5, Issue 6, November 2022., 2022
Abstract Background and Objective Before and after the fandom, the pattern of education has difficulty in accepting the requirements of the MZ generation with very intense changes. Individual differences between students and different educational environments have more difficulties with the addition of practical subjects than general students.
Jooyoung Lee, Ki Han Kwon
wiley   +1 more source

Conversación con Juan José Lahuerta, en torno al estudiante de arquitectura Antoni Gaudí

A&P Continuidad, 2022
El rescate de los dibujos escolares de un Antonio Gaudí estudiante es una llave para abrir esta conversación. A partir de ellos se indaga en el mito del genio centrado en la figura de este arquitecto catalán.
Juan José Lahuerta, Jorge Nudelman, Ana Cravino, María Claudina Blanc   +3 more
doaj   +1 more source

Recovering industrial heritage: restoration of the wine cellar cooperative in Falset (Catalonia, Spain) [PDF]

, 2019
Awareness regarding conservation of industrial heritage is recent. Several policies have been adopted to start protecting these buildings because of their historic, artistic and scientific values.
Cornadó Bardón, Còssima, Cuerva Contreras, Eva, Urbano, Judith   +2 more
core   +2 more sources