Results 201 to 210 of about 197,248 (298)

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Adverse childhood experiences and risk of living with HIV among lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ+) people: a cross-sectional study. [PDF]

Lancet Reg Health West Pac
Yang J, Liu L, Wang J, Xu Y, Zhao P, Wang Y, Du P, Tucker JD, Baral S, Geng EH, Wang X, Song H, Wu D.   +12 more
europepmc   +1 more source

Electrostatic Potential Complementarity for Thickness‐Tolerant Cathode Interlayers in High‐Efficiency Organic and Tandem Solar Cells

Advanced Science, EarlyView.
Two model molecules — trimesic acid (TMA) and phloroglucinol (PG) — with opposite central electrostatic potential (ESP) distributions are employed to elucidate how molecular electrostatic interactions regulate the cathode interlayer (CIL) PDINN. Electrostatic potential complementarity is revealed as the intrinsic origin of thickness sensitivity in CILs,
Xiaoman Ding, Dana Mukasheva, Jiaxu Che, Guangye Zhang, Xiuze Hei, Haoran Lin, Jie Lv, Patrick Fong, Zhiwei Ren, Annie Ng, Mingjian Yuan, Hongyu Zhang, Gang Li, Hanlin Hu   +13 more
wiley   +1 more source

Inclusive Language for Inclusive Care-A Proposal for an LGBTQI⁺ Glossary for European Neurologists. [PDF]

Eur J Neurol
Donzuso G, Ferretti MT, Pasini F, Cicero CE, Arabia G, de Visser M, Russell CB, Ramankulov D, Sander A, Nicoletti A, European Academy of Neurology (EAN) Coordinating Panel on Diversity, Equity and Inclusion in Neurology.   +11 more
europepmc   +1 more source

Synergistic Organic–Inorganic Interface Engineering for Stable Zinc Metal Anodes in Aqueous Batteries

Advanced Science, EarlyView.
A multifunctional mercaptosuccinic acid enables an ultrathin organic–inorganic SEI (Zn‐S‐RCOOH) that synergistically regulates interfacial water and accelerates Zn2+ transport. The optimized hydrogen‐bond environment and ZnS‐guided deposition suppress dendrites, corrosion, and by‐product formation, delivering ultrastable Zn cycling and high‐performance
Huaichong Sun, Yimin Chen, Jianwei Lu, Xiyuan Zhong, Zhihong Luo, Kaiwen Yang, Kun Luo, Aamir Shahzad, Muhammad Naveed Anjum, Weiwei Lei, Dan Liu, Aijing Ma   +11 more
wiley   +1 more source

Commentary on PURPOSE-1 and PURPOSE-2 trials of lenacapavir: a breakthrough in HIV prevention. [PDF]

Ann Med Surg (Lond)
Idrees M, Iftikhar H, Sohail F, Jadoon M, Khan MH.   +4 more
europepmc   +1 more source

One‐Step, High‐Removal‐Rate and Low‐Damage Chemical Mechanical Polishing of InP Enabled by Hydrolysis Activated PF6− with In Situ Fluoride Passivation

Advanced Science, EarlyView.
In this work, we propose a CMP method for InP using NH4PF₆, which hydrolyzes under In3+ catalysis to form reactive species. These convert InP into low‐binding‐energy fluorides, facilitating removal and dissolution. The process delivers high material removal rates, smooth surfaces, and fluorine passivation that lowers defect density and improves ...
Shigong Fu, Jianwei Zhou, Chenwei Wang, Yanchao Ge, Chong Luo, Yuhang Qi   +5 more
wiley   +1 more source

Recommendations from Black gay and bisexual men for developing a public health campaign to promote awareness of long-acting injectable PrEP within their community. [PDF]

Cult Health Sex
Santillan M, Nieto O, Segura-Bermudez JR, Rosenberg-Carlson EP, Motchoffo CS, Üsküp DK, Brooks RA.   +6 more
europepmc   +1 more source

Substrate‐Affinitive P‐Type Azapolycyclic Photosensitizer for Chemoselective Nitrilization Under Mild Conditions

Advanced Science, EarlyView.
We developed a series of quinoxalinoquinoxaline (QQ) photosensitizers featuring high and tunable excited‐state reduction potentials (E(PC•+/PC*) = –1.76 to –2.05 V vs. SCE). Their hydrogen‐bonding interaction with carbonyl substrates enables selective single‐electron transfer events for selective nitrilization of 1° amides, offering a tunable ...
Seongwoo Bae, Dongwook Kim, Jinwoo Kim
wiley   +1 more source