Results 201 to 210 of about 18,264 (257)

Normative evolution and institutional challenges of reproductive health of trans men and transmasculine people in Brazil: a scoping review. [PDF]

Cad Saude Publica
Austregésilo ND, Sampaio DB, Melo MSA, Marques VCLMM, Moretti EC, Ferreira CWS, Barbosa LMA.   +6 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Current State of LGBTQIA+ Health Education in Low- and Middle-Income Countries: A Narrative Review of Educational Gaps in Transgender, Intersex/Differences of Sex Development (DSD), and Sexual and Gender Minority Healthcare. [PDF]

Cureus
Aslam A, Fatima N, Khan A, Mubasher M, Haq TU, Jahanzaib M, Khan MA, Khawaja AA, Saeed H, Mehmood Qadri H.   +9 more
europepmc   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

[Biomedicalization and responses to aids in Brazil: research notes]. [PDF]

Hist Cienc Saude Manguinhos
Monteiro S, Brigeiro M.
europepmc   +1 more source

Physics‐Guided Descriptors Enable Data‐Efficient Prediction of Battery Coulombic Efficiency

Advanced Science, EarlyView.
This work integrates multiscale simulations with data‐driven approaches to predict Coulombic efficiency (CE). Multiscale simulations of battery systems are performed to extract Physics‐Guided descriptors and construct a dataset. Machine learning models trained on this dataset are then subjected to interpretable analysis to identify the most influential
Qintao Sun, Xuewei Gu, Yulin Jie, Hao Yang, Shuhong Jiao, Chao Tang, Yangping Sheng, Yuhao Lu, Ruiguo Cao, Tao Cheng   +9 more
wiley   +1 more source

R. Spitzer and the depathologization of homosexuality: some considerations on the 50th anniversary. [PDF]

World Psychiatry
Wakefield JC.
europepmc   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Development and validity of an educational booklet on LGBT+ health in Primary Health Care. [PDF]

Rev Bras Enferm
West MGLN, Araújo EC, Vilar CMLN, Batista MAL, Pereira DMR.   +4 more
europepmc   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

Advanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg, Anastasia Lopatina, Hao Ruan, Tom Scheidt, Simone Mosna, Emre Pekbilir, Julia Bieber, Frank Schäfer‐Depoix, Katharina Landfester, Carla Schmidt, Martin M. Möckel, Svenja Morsbach, Friederike Schmid, Dorothee Dormann, Lukas Stelzl, Martin Girard, Edward A. Lemke   +16 more
wiley   +1 more source