Results 21 to 30 of about 61,459 (138)
Functional and behavioral restoration of vision by gene therapy in the guanylate cyclase-1 (GC1) knockout mouse. [PDF]
Recessive mutations in guanylate cyclase-1 (Gucy2d) are associated with severe, early onset Leber congenital amaurosis-1(LCA1). Gucy2d encodes guanylate cyclase (GC1) is expressed in photoreceptor outer segment membranes and produces cGMP in these cells.
Sanford L Boye +9 more
core +1 more source
Neurocalcin δ Modulation of ROS-GC1, a New Model of Ca2+ Signaling† [PDF]
ROS-GC1 membrane guanylate cyclase is a Ca(2+) bimodal signal transduction switch. It is turned off by a rise in free Ca(2+) from nanomolar to the semicromolar range in the photoreceptor outer segments and the olfactory bulb neurons; by a similar rise ...
Sharma, Rameshwar +3 more
core +1 more source
Plankton blooms over the annual cycle shape trophic interactions under climate change
Understanding species phenology and temporal co‐occurrence across trophic levels is essential to assess anthropogenic impacts on ecological interactions. We analyzed 15 yr of monitoring data to identify trends and drivers of timing and magnitude of bloom‐
Kinlan M. G. Jan +3 more
doaj +1 more source
The Gluconobacter phage GC1 is a novel member of the Tectiviridae family isolated from a juice sample collected during dry white wine making. The bacteriophage infects Gluconobacter cerinus, an acetic acid bacterium which represents a spoilage ...
Olivier Claisse +11 more
core +1 more source
Application of RNA-targeted CRISPR/CasRx system in mouse spermatogonia cell line GC1-spg [PDF]
Objective To investigate the application of CRISPR/CasRx mediated gene knockdown at the RNA level in mouse spermatogonia cell line GC1-spg. Methods The EF1a core promoter.
LI Meng-zhen, LIU Jun, ZOU Ding-feng, MIAO Shi-ying, WANG Lin-fang, SONG Wei, LI Kai
core
Establishing fluvial silicon regimes and their stability across the Northern Hemisphere
Fluvial silicon (Si) plays a critical role in controlling primary production, water quality, and carbon sequestration through supporting freshwater and marine diatom communities.
Keira Johnson +18 more
doaj +1 more source
ZB-Format : ZB 1581 - [2270] [PDF]
ZB-FORMAT : ZB 1581 - [2270] Zeitschriften-Signaturenverzeichnis (-) ZB-Format : ZB 1581 - [2270] ([8]) ( - ) Cover ( - ) Titelseite (1) ZB 1581 bis ZB 1599 (2) Zb 1600 bis ZB 1699 (2) ZB 1700
core
Enhanced stream greenhouse gas emissions at night and during flood events
Headwater streams play a large role in aquatic greenhouse gas emissions. Carbon dioxide (CO2) and dissolved oxygen in streams often undergo changes through diel cycles. However, methane (CH4) and nitrous oxide (N2O) have unknown diel dynamics.
Rebecca L. Woodrow +7 more
doaj +1 more source
A Forward Error Compensation Approach for Fault Resilient Deep Neural Network Accelerator Design
Deep learning accelerator is a key enabler of a variety of safety-critical applications such as self-driving car and video surveillance. However, recently reported hardware-oriented attack vectors, e.g., fault injection attacks, have extended the threats
Chip-Hong Chang +3 more
core +1 more source

