Results 121 to 130 of about 13,926 (236)

Smart Design: Integrating Artificial Intelligence and Gene Editing for Advanced mRNA Therapeutics

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The challenges of mRNA therapy and the application of artificial intelligence and gene editing in the field of mRNA drugs. ABSTRACT Artificial intelligence (AI) and gene editing are increasingly being applied to the design and evaluation of mRNA therapeutics.
Haixing Shi, Shengbin Liu, Danni Dai, Shanhui Jiang, Tingchen Tian, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Fang Liu, Xue Tang, Xin Jiang, Xiangrong Song   +11 more
wiley   +1 more source

Muscle Strength, Balance, and Indoor Mobility in Oculopharyngeal Muscular Dystrophy: An Exploratory Canadian Multicenter Study

Muscle &Nerve, Volume 74, Issue 3, Page 656-668, September 2026.
ABSTRACT Introduction/Aims Oculopharyngeal muscular dystrophy (OPMD) is a neuromuscular disease presenting with dysphagia, ptosis, and proximal weakness. Muscle strength and indoor mobility capacity have rarely been studied using standardized clinical outcome assessments (COAs). The objectives of this study were to (1) document muscle strength, balance,
Nicolas Bélair, Jean‐Denis Brisson, Bernard Brais, Xavier Rodrigue, Hanns Lochmüller, Luc J. Hébert, Jessica MacGregor, Brenda Dennison, Isabelle Lessard, Isabelle Côté, Elise Duchesne, Cynthia Gagnon   +11 more
wiley   +1 more source

Genome–phenome association prediction using weighted deep matrix factorization with a multisource graph attention network

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Genome–phenome association (GPA) prediction can broaden the understanding of biological mechanisms underlying complex phenotypic traits (e.g., diseases and agronomic traits). Traditional deep matrix factorization (DMF)‐based GPA methods can integrate multiple data types and uncover nonlinear associations but often rely on low‐dimensional ...
Ran Duan, Wei Cao, Maozu Guo, Le Tian, Lingling Zhao   +4 more
wiley   +1 more source

Multi‐Modal AI Approach in Depression Detection and Treatment: A Systematic Review of Last Decade

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 3, September 2026.
Overview of multimodal approaches for depression detection and treatment. ABSTRACT Depression is a common and devastating mental health illness with serious personal and societal consequences. Despite advancing treatment techniques, there are still hurdles in the effective diagnosis and treatment of depression, such as prompt diagnosis, personalized ...
Smith K. Khare, Esmaeil S. Nadimi, U. Rajendra Acharya, Victoria Blanes‐Vidal   +3 more
wiley   +1 more source

Large Language Models in Electrical and Computer Engineering Education: Opportunities, Challenges and the Road Ahead

European Journal of Education, Volume 61, Issue 3, September 2026.
ABSTRACT Electrical and Computer Engineering (EE/CE) education encompasses the rigorous study of electronic systems, computing architectures, embedded platforms, signal processing and hardware–software integration. Its inherently multidisciplinary nature demands mastery of mathematical modelling and experimental validation skills that pose substantial ...
Abdulmalik Alwarafy
wiley   +1 more source

DHA-eGCN: Differential Hyperedge Attention-Enhanced Graph Convolution Network for Skeleton-Based Human Action Recognition. [PDF]

Sensors (Basel)
Nugroho OIA, Lie WN.
europepmc   +1 more source

Impacts of Pasture Conversion to Sugarcane on Water Fluxes and Water Use Efficiency in the Southeastern US

GCB Bioenergy, Volume 18, Issue 9, September 2026.
Sugarcane expansion, poised to reshape the Southeastern US bioenergy landscape, has uncertain ecohydrological implications following pasture conversion. Compared with improved and semi‐native pastures, sugarcane showed more conservative water use, stronger stomatal sensitivity to atmospheric water demand, higher evaporation, and greater water‐use ...
Sneha Bandyopadhyay, Elena Blanc‐Betes, Cole Walton, Tess Rutstein, Carl J. Bernacchi, Evan H. DeLucia, Elizabeth H. Boughton, Amartya Saha, Wendy H. Yang, Caitlin E. Moore, Nuria Gomez‐Casanovas   +10 more
wiley   +1 more source

iLDA-SGCN: Identifying Associations Between Age-Related Diseases and Long Non-Coding RNAs Using Dual Graph Convolutional Networks. [PDF]

Aging Cell
Guo Y, Qiu S, Zhang Z, Guo J, Liang H, You H, Lu F, Xu Y, Hu Y.   +8 more
europepmc   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, Volume 13, Issue 43, 3 August 2026.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Exploratory Identification of Gene Copy Number Cut-Off for NGS-Based <i>MET</i> Amplification Assessment and Clinical Relevance to MET Inhibitor Outcomes in Non-Small-Cell Lung Cancer. [PDF]

Lung Cancer (Auckl)
Liu SM, Xie Z, Yan L, Jie GL, Deng JY, Zhang Q, Huang Z, Wang J, Zhang Z, Shao Y, Meng H, Zhang Y, Zhang XC, Chen HJ, Zhong WZ, Zhou Q, Wu YL.   +16 more
europepmc   +1 more source