Results 241 to 250 of about 40,634 (335)

Surufatinib plus anti‐PD‐1/PD‐L1 antibody as second‐line therapy for advanced biliary tract cancer: A single‐centre investigator‐initiated trial

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Abstract Objective To explore the efficacy and safety of surufatinib in combination with anti‐PD‐1/PD‐L1 antibodies (with or without chemotherapy) in patients with advanced BTC after failure of first‐line treatment. Methods 24 patients with advanced BTC who failed first‐line treatment were admitted to our centre from March 2023 to August 2024 and ...
Xinni Chen   +7 more
wiley   +1 more source

Distinct Roles of Dopamine and Noradrenaline in Physical Fatigue

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 2, February 2026.
ABSTRACT This triple‐blinded randomized crossover study investigated the roles of dopamine (DA) and noradrenaline (NA) in regulating exercise performance and fatigue using acute pharmacological manipulation. Eighteen healthy adults (9 males and 9 females; mean age = 23.4 ± 2.2 years) completed three experimental conditions.
Y. Laurisa Arenales Arauz   +8 more
wiley   +1 more source

SARA module (GCP + GMP

open access: yes
SARA module (GCP + GMPThis deliverable is composed by HW and SW which still remains property of SISTEMATICA.
openaire   +1 more source

Reduction in Earth's carbon budget imbalance. [PDF]

open access: yesNat Commun
Pandey S   +6 more
europepmc   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

open access: yesEpilepsia Open, Volume 11, Issue 1, Page 291-321, February 2026.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha   +27 more
wiley   +1 more source

Therapeutic Potential of Saikosaponins in MASLD and Cross‐Organ Protection: A Research Update

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
This review systematically outlines the multi‐target mechanisms of Saikosaponins (SSs) against MASLD, encompassing the regulation of lipid metabolism, insulin resistance, and inflammatory response. Furthermore, it highlights their novel cross‐organ protective effects on the cardiovascular, renal, and central nervous systems, providing therapeutic ...
Jiayao Xiong   +5 more
wiley   +1 more source

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