Results 161 to 170 of about 19,021 (331)

Research Staff's Experiences of Applying the UNCRC in Clinical Research Involving Young Children—An Ongoing Process of Ethical Judgement

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim An estimated five million children under the age of five die each year, largely from preventable causes. Clinical research involving young children is essential for improving child health, but is ethically complex. The United Nations Convention on the Rights of the Child (UNCRC) provides a framework for protecting children's rights and ...
Anna Karin Bernhardsson, Anna Gustafsson
wiley   +1 more source

Clinical trial: The Effect on Intragastric pH and Pharmacokinetics of the PCAB Linaprazan Glurate in Healthy Subjects After Repeat‐Dose Administration for up to 14 Days

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this Phase 1 study, linaprazan glurate (LG) demonstrated rapid onset of intragastric acid suppression, achieving a pH > 4 within 10 to 60 min, and maintained pH control, with a 24‐h pH > 4 holding time ratio above 95% at 50 mg and 75 mg twice‐daily doses. AUC and Cmax of linaprazan, the main metabolite of LG, increased in proportion to LG dose.
Kajsa Larsson   +7 more
wiley   +1 more source

Post‐Trial Responsibilities for Participants Implanted With Neurosurgical Devices: A Qualitative Study

open access: yesBioethics, EarlyView.
ABSTRACT The issue of post‐trial responsibility is about what is owed to research participants after a clinical trial ends, who is responsible, and how long this responsibility must endure. Despite two decades of international guidance on this issue, research involving novel high‐risk interventions—such as implantable neurotechnologies—raises ...
Nathan Higgins   +2 more
wiley   +1 more source

GCP [PDF]

open access: yes, 2019
openaire   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

open access: yesBJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui   +2 more
wiley   +1 more source

High‐Gloss SVBRDF Capture Using Bounce Light

open access: yesComputer Graphics Forum, EarlyView.
Abstract Reflectance capture aims at the visual reproduction of an object under varying illumination. Past works differ substantially in their experimental overhead, from single‐ or few‐image approaches, that employ significant (often learned) priors at the expense of biased reconstructions, to more accurate approaches that tend to be time‐consuming ...
Tomáš Iser   +2 more
wiley   +1 more source

Contouring Signed Distance Fields by Approximating Gradients

open access: yesComputer Graphics Forum, EarlyView.
Abstract Signed distance fields are often represented by discrete samples (e.g., on a grid). Recovering the contour implicitly represented by the distance samples requires an approximation algorithm. Several recent approaches have shown that exploiting the information carried in each distance sample by explicitly constructing a surface point gives ...
M. Kohlbrenner, M. Alexa
wiley   +1 more source

Methods of GCP ability training for residents

open access: yesAsian Journal of Surgery, 2023
Guang-Min Xu   +3 more
openaire   +3 more sources

Η χρησιμότητα της ίδρυσης εδαφικών σημείων ελέγχου (GCPs) στη φωτογραμμετρική επεξεργασία δεδομένων από ΣμηΕΑ

open access: yes
Η παρούσα διπλωματική εργασία εκπονήθηκε στο πλαίσιο του προπτυχιακού προγράμματος σπουδών του Τμήματος Γεωλογίας και Γεωπεριβάλλοντος, του Εθνικού και Καποδιστριακού Πανεπιστημίου Αθηνών, στον Τομέα Γεωγραφίας και Κλιματολογίας και συγκεκριμένα στο ...
ΜΕΪΜΑΡΟΓΛΟΥ ΣΑΒΒΑΣ-ΕΦΡΑΙΜ
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