Results 211 to 220 of about 6,323 (304)

Regulatory Challenges and Opportunities for Cell‐Derived Extracellular Vesicles in Pharmaceutical Development: A European and Global Perspective

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
EV‐based therapeutics are advancing worldwide, but regulatory classification and development expectations remain inconsistent across jurisdictions. This review maps challenges in quality, potency, comparability, safety, clinical design, and ethical/legal oversight, and argues for consistent use of existing medicinal‐product frameworks. We emphasize the
Tania Limongi, Paola Milla, Barbara Stella, Silvia Arpicco   +3 more
wiley   +1 more source

Additive effect of coronary artery stenosis on left ventricular myocardial strain in patients with essential hypertension: an analysis of cardiac MRI feature tracking. [PDF]

Quant Imaging Med Surg
Yan WF, Wen LY, Yang ZG, Xu R, Jiang YN, Yu SQ, Zhang G, Wang J, Li Y.   +8 more
europepmc   +1 more source

Torque Teno Virus Dynamics in Plasma and BAL of COVID‐19 ARDS Patients With and Without ECMO

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT Extracorporeal membrane oxygenation (ECMO) is used to manage severe acute respiratory distress syndrome (ARDS) and is associated with immune modulation. Torque teno virus (TTV) has been proposed as a surrogate marker of immune competence, but it remains unclear whether ECMO influences TTV levels.
Armin Marcus Bumberger, Marie‐Theres Kastner, Riem Gawish, Lina Rüsing, Iwan Wukits, Monika Breuer, Robert Strassl, Christoph Steininger, Oliver Robak   +8 more
wiley   +1 more source

Development of an HRM-qRT-PCR platform for fast and cost-effective genotyping of infectious bronchitis virus in Egypt. [PDF]

Sci Rep
Ali A, Prince A, Aljuaydi SH, Yassin AM, Khalifa R, Dardir S, Moussa SZ.   +6 more
europepmc   +1 more source

Digital Phenotyping and Lifestyle Intervention in Patients With Myasthenia Gravis (DIG‐MG): A Randomized Controlled Trial of Feasibility, Adherence, and Effects on Fatigue

Muscle &Nerve, Volume 74, Issue 1, Page 92-102, July 2026.
ABSTRACT Introduction/Aims Physical activity and sleep influence fatigue in myasthenia gravis (MG), and digital health technologies (DHT) enable objective monitoring of these behaviors in daily life. Using this approach, we evaluated whether a lifestyle intervention targeting physical activity or sleep hygiene could reduce fatigue in MG.
Maja Norling, Niclas Eriksson, Elisabet Westerberg, Ingela Nygren, Klara Norman, Julia Hedberg, Sui H. Wong, Susanna Jernelöv, Pernilla Åsenlöf, Anna Rostedt Punga   +9 more
wiley   +1 more source

Defining chronic pain impact levels: a patient-clinician approach using PROMIS® pain interference scores. [PDF]

J Patient Rep Outcomes
Cook KF, You DS, Korff MV, Mackey SC.
europepmc   +1 more source

Capturing the Multi‐Decadal Evolution of Glacier–Permafrost Interactions in a High‐Alpine Environment (Ritord, Western Swiss Alps)

Permafrost and Periglacial Processes, Volume 37, Issue 3, Page 473-497, July/September 2026.
ABSTRACT This study investigates the multi‐decadal evolution of a glacier forefield under permafrost conditions in the Combins Massif (western Swiss Alps). A multi‐method approach based on historical and recent datasets is used to analyze its landform components.
Julie Wee, Hanne Hendrickx, Sebastián Vivero   +2 more
wiley   +1 more source

PK and PK/PD Modeling of Bcl2 Inhibitor S65487 in Patients With AML and Investigation of Nonlinearity With Microdosing

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
ABSTRACT This work aims to assess the S65487‐induced disruption of the B‐cell lymphoma‐2 (Bcl2)/Bcl2‐like protein 11 (Bim) complex at therapeutic doses via a pharmacokinetic/pharmacodynamic model and to reconcile pharmacokinetic data from microdoses and therapeutic doses in a single population pharmacokinetic model. The first model consists of a linear
Chloé Burlot, François Riglet, Mathilde Romagnoli, Ariane Leconte, Audrey Delmas, Antonin Schmitt, Sylvain Fouliard   +6 more
wiley   +1 more source

Uncertainty of Object Points Monoplotted from Terrestrial Images. [PDF]

J Photogramm Remote Sens Geoinform Sci
Mikolka-Flöry S, Ressl C, Pfeifer N.
europepmc   +1 more source

Meander‐Bend Erosion Dynamics Along a Gravel‐Bed River: Insights From Short‐Term UAV Monitoring

River Research and Applications, Volume 42, Issue 6, Page 1223-1238, July 2026.
ABSTRACT Riverbank erosion is a natural process in meandering rivers that contributes to sediment supply and geomorphic diversity, yet it can threaten infrastructure and human activities within the floodplain. Recently, many studies have used high‐resolution remote sensing technologies to measure bank erosion, but they often focus on technical aspects ...
Katarina Pavlek, Mateo Gašparović, Tomáš Galia   +2 more
wiley   +1 more source