Results 231 to 240 of about 7,059 (300)

Beyond Blind Trust in Hospital Data Warehouses: Evaluating Real‐World Data Accountability

Learning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Introduction The reliability of real‐world evidence (RWE) depends on data accuracy and secondary users' ability to evaluate how data are generated and transformed. Although recent frameworks emphasize provenance, transparency, and auditability, their practical assessment in routine hospital settings remains unclear.
Akemi Morohashi, Satoshi Yamashita, Takahiro Imaizumi, Takuto Sano, Yachiyo Kuwatsuka, Masahiko Ando, Yoshimune Shiratori   +6 more
wiley   +1 more source

Clinical and cardiac magnetic resonance imaging features for differentiation between acute myocardial infarction with and without obstructive coronary arteries. [PDF]

Quant Imaging Med Surg
Shen LT, Yang ZG, Guo YK, Qian WL, Yan WF, Jiang YN, Shi K, Li Y.   +7 more
europepmc   +1 more source

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

Pediatric Anesthesia, Volume 36, Issue 10, Page 1308-1315, October 2026.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud, Arash Afshari, Lau Romlund Halgreen, Kristian Østergaard Nielsen, Lars Peter Kloster Andersen   +4 more
wiley   +1 more source

G-quadruplexes as a source of vulnerability in BRCA2-deficient granule cell progenitors and medulloblastoma. [PDF]

Proc Natl Acad Sci U S A
Keahi DL, Sanders MA, Paul MR, Webster ALH, Fang Y, Wiley TF, Shalaby S, Carroll TS, Chandrasekharappa SC, Sandoval-Garcia C, MacMillan ML, Wagner JE, Hatten ME, Smogorzewska A.   +13 more
europepmc   +1 more source

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

European Journal of Haematology, Volume 117, Issue 4, Page 922-935, October 2026.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio, Antonio José Martinez‐Mellado, Jonathan Kiwitt‐Cárdenas, José G. Clavel, Bartolomé García‐Perez, Pedro Castro, Maribel Diaz‐Ricart, Andrés Carrillo‐Alcaraz, Amparo López‐Bernús, Enrique Bernal Morell, Aychel Roura, Sonia Marín, Francisco‐José Ruiz‐López, Elena Solana‐Martinez, Domingo Martinez‐Baño, Carlos L. Albacete Moreno, Enriqueta Andreu Soler, Adrián Tellez Santoyo, Sara Fernández Méndez, Jose A. Noguera Velasco, Iria Cebreiros Lopez, Andrés Parrilla, Alberto Espuny‐Miró, David García‐Bernal, Miguel Blanquer, Andrés Sánchez‐Salinas, Francisca Iniesta, Cristina Hernandez Garcia, Manuel Muro, Alfredo Minguela Puras, Antonio Moreno‐Docón, Alberto M. Torres‐Cantero, Maria Munoz Garcia, Manuel Serrano, Massimo Iacobelli, Carmelo Carlo‐Stella, Lee‐Jen Wei, Paul G. Richardson, José M. Moraleda   +38 more
wiley   +1 more source

Involving People With Dementia in Research: Contributions, Barriers and Evaluation From a Meta‐Synthesis and Qualitative Interview Study

Health Expectations, Volume 29, Issue 5, October 2026.
ABSTRACT Background Patient and Public Involvement and Engagement (PPIE) can enhance the relevance, acceptability and quality of research; however, its meaningful implementation in dementia research remains insufficiently understood. Aim (1) To identify methodological procedures for involving people with dementia (PwD) across the research lifecycle ...
Jörg Meisser, Susanne de Wolf‐Linder, Christina Ramsenthaler   +2 more
wiley   +1 more source

Patient Safety Competencies, Clinical Learning Environment and Unfinished Care From the Perspective of Nursing Students: A Multinational Study

Journal of Clinical Nursing, Volume 35, Issue 10, Page 4333-4351, October 2026.
ABSTRACT Aim To assess perceived patient safety competencies among nursing students and to examine their associations with their perceptions regarding clinical learning environment and unfinished nursing care. Design An international comparative cross‐sectional study.
Dominika Kohanová, Elena Gurková, Alvisa Palese, Daniela Bartoníčková, Lenka Mazalová, Aysel Özsaban, Aysun Bayram, Seher Basaran‐Acil, Öznur Ispir Demir, Stefania Chiappinotto   +9 more
wiley   +1 more source

The transient external granular layer in human foetal cerebellum: insights into neurogenesis, genetic regulation, and developmental disorders. [PDF]

Anat Cell Biol
Kausar A, Nayak SS, Marpalli S, Veeresh, George BM, Hosapatna M.   +5 more
europepmc   +1 more source

Development of a Machine Learning Model to Predict Short Duration HCV Treatment Response

Journal of Viral Hepatitis, Volume 33, Issue 10, October 2026.
ABSTRACT Standard durations of direct acting antivirals (DAAs; 8–12 weeks) can be a barrier to HCV treatment initiation and completion among marginalized populations. This study developed and internally validated a machine learning model to predict short‐duration (4–6 weeks) DAA response using baseline clinical factors with potential to improve ...
Joanne M. Carson, Sebastiano Barbieri, Andrey Verich, Elise Tu, Andrew Lloyd, Gregory J. Dore, Gail V. Matthews, Marianne Martinello   +7 more
wiley   +1 more source