Results 111 to 120 of about 6,323 (304)

Sargassum Lung Syndrome: Air Flow Obstruction and Bronchial Inflammation Are Observed After Prolonged Exposure to Sargassum Gas Emissions in the Eastern Caribbean

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen   +9 more
wiley   +1 more source

GCP inspection by Roszdravnadzor

open access: yesКачественная клиническая практика, 2018
Государственные органы определяют правила проведения клинических исследований лекарственных средств, поэтому обязаны непосредственно контролировать их проведение. Основная форма контроля за клиническими исследованиями лекарственных препаратов со стороны государства - инспекция.
Belousov D.Yu.   +4 more
openaire   +2 more sources

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Modelling the Four‐Dimensional Power Line Sag Dynamics by Point Signature in Time‐Series Synthetic‐Aperture Radar Images

open access: yesHigh Voltage, EarlyView.
ABSTRACT Power lines in synthetic‐aperture radar (SAR) images are reflected as point signatures, which fluctuate annually in both the azimuth and range directions. A novel framework is proposed in this paper to evaluate the four‐dimensional dynamic status of power line sag using those point signatures in time‐series SAR images.
Sijie Ma   +4 more
wiley   +1 more source

Digital green synergies: linking green cyber-physical systems, green supply chains integration, and green business intelligence to boost SMEs sustainability

open access: yesCleaner Logistics and Supply Chain
This study investigates the synergistic effects of Green Cyber-Physical Systems (GCPS), Green Supply Chain Integration (GSCI), and Green Business Intelligence (GBI) on enhancing Sustainable Performance (SP) within Saudi Arabian SMEs across manufacturing,
Mohammad Nurul Alam   +5 more
doaj   +1 more source

GCP [PDF]

open access: yes, 2002
Mario Zuehlke, Hartmut Koenig
openaire   +1 more source

Modern Management of the Menopause: Are We Measuring What Matters?

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Assess uptake of the Core Outcomes in Menopause (COMMA) core outcome sets (COS) and examine whether frontline treatments for vasomotor and genitourinary symptoms have been evaluated against these key outcomes. Design Methodological review. Setting Published literature and international clinical trial registries.
Joscelyn Gan   +7 more
wiley   +1 more source

Effect of Intramuscular Adrenaline on Histamine‐Induced Hypotension: A Randomised Placebo‐Controlled Pilot Trial

open access: yesAllergy, EarlyView.
Histamine infusions induce reproducible severe hypotension. Intramuscular adrenaline showed ‘supposedly therapeutic’ plasma concentrations but did not produce a sustained clinically relevant improvement in shock in the majority of recipients. These findings question adrenaline pharmacokinetic surrogate thresholds and support the need for faster and ...
Matthias Weiss‐Tessbach   +12 more
wiley   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

open access: yesAllergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian   +18 more
wiley   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

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