Results 51 to 60 of about 379,851 (308)

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

ANALYSIS AND ASSESSMENT OF STRUCTURAL CHANGES IN RESEARCH AND DEVELOPMENT ACTIVITIES BY REGIONS IN BULGARIA

Trakia Journal of Sciences
Investments in Research and Development (R&D) are a vital aspect of the modern economy and are regarded as a strategic tool for economic transformation, enhancing competitiveness, and transitioning toward a knowledge and innovation-based economy. The
V. Kertikova, Iv. Stoycheva
doaj   +1 more source

Structures of NodZ α1,6-fucosyltransferase in complex with GDP and GDP-fucose [PDF]

Acta Crystallographica Section D Biological Crystallography, 2012
Rhizobial NodZ α1,6-fucosyltransferase (α1,6-FucT) catalyzes the transfer of the fucose (Fuc) moiety from guanosine 5'-diphosphate-β-L-fucose to the reducing end of the chitin oligosaccharide core during Nod-factor (NF) biosynthesis. NF is a key signalling molecule required for successful symbiosis with a legume host for atmospheric nitrogen fixation ...
Krzysztof, Brzezinski, Zbigniew, Dauter, Mariusz, Jaskolski   +2 more
openaire   +2 more sources

Analyzing the Effect of Knowledge-based Economy Indices on Countries’ GDP [PDF]

مدیریت بهره وری, 2012
The increasing importance of the role of knowledge in economy has led to “Knowledge-based economy”. Knowledge-based economy can be considered as a kind of economy in which the creation and application of knowledge play a major role in creating wealth ...
Kazem Amjadi, Gholamreza Rahbare banaeiyan, Gholamreza Soltani fesgendis   +2 more
doaj  

Optimized Land–Water Management Expands Afforestation Potential Under Land and Human Water‐Use Constraints

Advanced Science, EarlyView.
Human water demand constrains China's feasible afforestation potential more strongly than is commonly recognized, and future climate change further intensifies this limitation. Integrating land‐use optimization with water‐saving measures substantially expands feasible afforestation area and associated carbon sinks, revealing a practical pathway to ...
Binbin Huang, Fei Lu, Yuebo Su, Xuming Wang, Hua Zheng, Zhiyun Ouyang   +5 more
wiley   +1 more source

The State of Data for Services Productivity Measurement in the United States [PDF]

International Productivity Monitor, 2008
In this article, we present a brief history of the development of services industry data in the United States, review the substantial progress that has been made over the past decade and a half, and present recommendations for needed additional ...
Jack E. Triplett, Barry P. Bosworth
doaj  

GDP growth project [PDF]

, 2008
Study examines the economic structure and dynamics of the East Midlands and Yorkshire and Humber regions of the UK, using the logic of firm and labour agglomerations and their contribution to GDP as the basis for the ...
Johnson, A, Atherton, A
core  

Semi‐Artificial Photosynthesis Enables Light‐Driven Biomanufacturing in Non‐Photosynthetic Bacteria

Advanced Science, EarlyView.
A non‐invasive strategy exploits endogenous H2S metabolism in B. subtilis to drive in situ CdS biomineralization, enabling tight bio‐abiotic contact without genetic modification. Light harvested by the biomineralized nanoparticles powers NADPH regeneration, elevating 2’‐fucosyllactose and surfactin titres two‐ to three‐fold.
Jie Zheng, Anqi Tong, Wenxin Li, Meng Qiao, Yang Gu, Muhammad Sohail, Shan He, Sheng Yang, Xing Zhang   +8 more
wiley   +1 more source

Hemp Cultivation and Crop Diversification: Implications for Ecosystem Services in Kentucky

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This study examines the ecosystem benefits of expanding hemp cultivation by assessing its impact on crop diversity. Using scenario‐based simulations and fixed‐effect panel regressions with county‐level data in Kentucky, we find that increased hemp acreage tends to enhance crop diversity, improving water quality and bird diversity.
Yunsun Park, Seong D. Yun, Brandy E. Phipps, Tyler Mark, Craig Schluttenhofer   +4 more
wiley   +1 more source

APPLICATION OF ARIMA MODEL FOR FORECASTING NATIONAL ECONOMIC GROWTH: A FOCUS ON GROSS DOMESTIC PRODUCT DATA

Barekeng
This study aims to apply the Autoregressive Integrated Moving Average (ARIMA) model to predict national economic growth, specifically focusing on Gross Domestic Product (GDP) data. GDP data were collected from 2012 to 2023, categorized into training data
Elisabeth Brielin Sinu, Maria A Kleden, Astri Atti   +2 more
doaj   +1 more source